Research Article

A Nested Case-Control Study of Association between Metabolome and Hypertension Risk

Table 1

Baseline characteristic of study participants.

CharacteristicsIndividuals who developed
hypertension ()
Individuals with optimal
blood pressure ()

Age (years)52.1 ± 4.251.9 ± 4.10.84
Men (%)44.841.40.79
BMI (kg/m2)23.2 ± 2.624.0 ± 2.80.31
SBP (mmHg)110.8 ± 6.6110.2 ± 6.40.72
DBP (mmHg)72.9 ± 4.172.4 ± 4.80.79
FBG (mg/dL)83.9 ± 12.782.4 ± 7.90.60
TG (mg/dL)84 (65, 106)96 (64, 111)0.64
TC (mg/dL)202.9 ± 35.1199.9 ± 30.00.73
LDL-C (mg/dL)121.1 ± 30.3116.5 ± 23.10.52
HDL-C (mg/dL)56.6 ± 10.760.7 ± 15.90.26
CRP (mg/dL)0.60 (0.30, 0.81)0.68 (0.25, 1.17)0.30
Creatinine (mg/dL)0.99 ± 0.170.96 ± 0.180.54
Smoking (%)20.710.30.47
Drinking (%)13.86.90.67

BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; FBG: fasting blood glucose; TG: triglycerides; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; CRP: C reactive protein. Data are expressed as a percent for categorical variables, as mean ± standard deviation for continuous variables in cases of normally distributed data, and as medians (interquartile ranges) otherwise. values for the difference between two groups.