Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2016, Article ID 7842587, 7 pages
http://dx.doi.org/10.1155/2016/7842587
Review Article

Association between Toll-Like Receptor 4 Polymorphisms and Systemic Lupus Erythematosus Susceptibility: A Meta-Analysis

1Department of Nephrology, First Affiliated Hospital of Xiamen University, Xiamen, Fujian 361003, China
2Department of Nephrology, Longyan First Hospital Affiliated to Fujian Medical University, Longyan, Fujian 36400, China
3Arogya Health Home, Arthritis and Rheumatic Diseases Treatment Center, Jawalakhel, Lalitpur, Nepal
4Department of Infectious Disease Control, Xiamen Center for Disease Control and Prevention, Xiamen, Fujian 361021, China
5Department of Nephrology, Xiamen City Fifth Hospital, Xiamen, Fujian 361101, China

Received 25 May 2016; Accepted 3 August 2016

Academic Editor: Abdul M. Tyagi

Copyright © 2016 Weiping Hu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Z. Wang, Y. Wang, R. Zhu et al., “Long-term survival and death causes of systemic lupus erythematosus in China: a systemic review of observational studies,” Medicine, vol. 94, article e794, 2015. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Choi, S. T. Kim, and J. Craft, “The pathogenesis of systemic lupus erythematosus-an update,” Current Opinion in Immunology, vol. 24, no. 6, pp. 651–657, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. E. C. Somers, W. Marder, P. Cagnoli et al., “Population-based incidence and prevalence of systemic lupus erythematosus: the michigan lupus epidemiology and surveillance program,” Arthritis and Rheumatology, vol. 66, no. 2, pp. 369–378, 2014. View at Publisher · View at Google Scholar · View at Scopus
  4. G. S. Cooper, M. A. Dooley, E. L. Treadwell, E. W. St. Clair, and G. S. Gilkeson, “Risk factors for development of systemic lupus erythematosus: allergies, infections, and family history,” Journal of Clinical Epidemiology, vol. 55, no. 10, pp. 982–989, 2002. View at Publisher · View at Google Scholar · View at Scopus
  5. H. A. Martens, I. M. Nolte, G. Van Der Steege et al., “An extensive screen of the HLA region reveals an independent association of HLA class I and class II with susceptibility for systemic lupus erythematosus,” Scandinavian Journal of Rheumatology, vol. 38, no. 4, pp. 256–262, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Lartigue, N. Colliou, S. Calbo et al., “Critical role of TLR2 and TLR4 in autoantibody production and glomerulonephritis in lpr mutation-induced mouse lupus,” The Journal of Immunology, vol. 183, no. 10, pp. 6207–6216, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. D. Moher, A. Liberati, J. Tetzlaff, and D. G. Altman, “Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement,” International Journal of Surgery, vol. 8, no. 5, pp. 336–341, 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. E. Sánchez, G. Orozco, M. Á. López-Nevot, J. Jiménez-Alonso, and J. Martín, “Polymorphisms of toll-like receptor 2 and 4 genes in rheumatoid arthritis and systemic lupus erythematosus,” Tissue Antigens, vol. 63, no. 1, pp. 54–57, 2004. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Bogaczewicz, T. Sobow, J. Bogaczewicz et al., “Toll-like receptor 4 gene polymorphism 1196 C/T does not influence the risk of neuropsychiatric systemic lupus erythematosus in Polish population—a preliminary report,” Lupus, vol. 22, no. 14, pp. 1504–1508, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. T. Dhaouadi, I. Sfar, Y. Haouami et al., “Polymorphisms of Toll-like receptor-4 and CD14 in systemic lupus erythematosus and rheumatoid arthritis,” Biomarker Research, vol. 1, article 20, 2013. View at Publisher · View at Google Scholar
  11. Y. Rupasree, S. M. Naushad, L. Rajasekhar, A. Uma, and V. K. Kutala, “Association of TLR4 (D299G, T399I), TLR9 -1486T>C, TIRAP S180L and TNF-α promoter (−1031, −863, −857) polymorphisms with risk for systemic lupus erythematosus among South Indians,” Lupus, vol. 24, no. 1, pp. 50–57, 2015. View at Publisher · View at Google Scholar · View at Scopus
  12. N. Nomura, N. Miyajima, T. Sazuka et al., “Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1,” DNA Research, vol. 1, no. 1, pp. 27–35, 1994. View at Publisher · View at Google Scholar · View at Scopus
  13. S. W. Brubaker, K. S. Bonham, I. Zanoni, and J. C. Kagan, “Innate immune pattern recognition: a cell biological perspective,” Annual Review of Immunology, vol. 33, pp. 257–290, 2015. View at Publisher · View at Google Scholar · View at Scopus
  14. H. Bosshart and M. Heinzelmann, “Targeting bacterial endotoxin: two sides of a coin,” Annals of the New York Academy of Sciences, vol. 1096, pp. 1–17, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. M. Wendel, R. Paul, and A. R. Heller, “Lipoproteins in inflammation and sepsis. II. Clinical aspects,” Intensive Care Medicine, vol. 33, no. 1, pp. 25–35, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. A. Sadanaga, H. Nakashima, M. Akahoshi et al., “Protection against autoimmune nephritis in MyD88-deficient MRL/lpr mice,” Arthritis & Rheumatism, vol. 56, no. 5, pp. 1618–1628, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. P. Rallabhandi, J. Bell, M. S. Boukhvalova et al., “Analysis of TLR4 polymorphic variants: new insights into TLR4/MD-2/CD14 stoichiometry, structure, and signaling,” Journal of Immunology, vol. 177, no. 1, pp. 322–332, 2006. View at Publisher · View at Google Scholar · View at Scopus
  18. R. Shimazu, S. Akashi, H. Ogata et al., “MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4,” Journal of Experimental Medicine, vol. 189, no. 11, pp. 1777–1782, 1999. View at Publisher · View at Google Scholar · View at Scopus
  19. T. Glück, J. Silver, M. Epstein, P. Cao, B. Farber, and S. M. Goyert, “Parameters influencing membrane CD14 expression and soluble CD14 levels in sepsis,” European Journal of Medical Research, vol. 6, no. 8, pp. 351–358, 2001. View at Google Scholar · View at Scopus
  20. N. C. Arbour, E. Lorenz, B. C. Schutte et al., “TLR4 mutations are associated with endotoxin hyporesponsiveness in humans,” Nature Genetics, vol. 25, no. 2, pp. 187–191, 2000. View at Publisher · View at Google Scholar · View at Scopus
  21. R. N. Douville, Y. Lissitsyn, A. F. Hirschfeld et al., “TLR4 Asp299Gly and Thr399ile polymorphisms: no impact on human immune responsiveness to LPS or respiratory syncytial virus,” PLoS ONE, vol. 5, no. 8, Article ID e12087, 2010. View at Publisher · View at Google Scholar · View at Scopus
  22. N. Yamakawa, U. Ohto, S. Akashi-Takamura et al., “Human TLR4 polymorphism D299G/T399I alters TLR4/MD-2 conformation and response to a weak ligand monophosphoryl lipid A,” International Immunology, vol. 25, no. 1, pp. 45–52, 2013. View at Publisher · View at Google Scholar · View at Scopus
  23. T. R. Hawn, A. Verbon, M. Janer, L. P. Zhao, B. Beutler, and A. Aderem, “Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease,” Proceedings of the National Academy of Sciences of the United States of America, vol. 102, no. 7, pp. 2487–2489, 2005. View at Publisher · View at Google Scholar · View at Scopus
  24. N. C. Suryadevara, V. S. K. Neela, S. Kovvali et al., “Genetic association of G896A polymorphism of TLR4 gene in leprosy through family-based and case-control study designs,” Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 107, no. 12, Article ID trt084, pp. 777–782, 2013. View at Publisher · View at Google Scholar · View at Scopus
  25. B. Ferwerda, M. B. McCall, S. Alonso et al., “TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans,” Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 42, pp. 16645–16650, 2007. View at Publisher · View at Google Scholar
  26. M. Kirchner, A. Sonnenschein, S. Schoofs, P. Schmidtke, V. N. Umlauf, and W. Mannhardt-Laakmann, “Surface expression and genotypes of Toll-like receptors 2 and 4 in patients with juvenile idiopathic arthritis and systemic lupus erythematosus,” Pediatric Rheumatology, vol. 11, article 9, 2013. View at Publisher · View at Google Scholar · View at Scopus