Research Article

17β-Estradiol Promotes Schwann Cell Proliferation and Differentiation, Accelerating Early Remyelination in a Mouse Peripheral Nerve Injury Model

Figure 2

E2 treatment accelerated early myelin formation in the nerve bridge site upon sciatic nerve transection. (a) Toluidine blue staining of the transverse semithin sections of the nerve bridge from injured sciatic nerves of control and E2-treated mice to illustrate myelin sheaths. Scale bars represent 25 μM (1000x). (b) Quantification of myelinated axons per 2500 μM2, based on (a) (; , ).
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