¹²⁵I Seeds Radiation Induces Paraptosis-Like Cell Death via PI3K/AKT Signaling Pathway in HCT116 Cells

Figure 3

¹²⁵I seeds radiation induced the morphological changes of HCT116 cells. (a) 48 h after exposure to 2 Gy of ¹²⁵I seeds radiation the morphology of HCT116 cells was detected under transmission electron microscopy. Control cell with normal mitochondria and ER, which was denoted by white arrows or black arrowheads, respectively. Irradiated cells showed cytoplasmic vacuolation. Mitochondria were denoted by white arrowheads. (b) DAPI staining of HCT116 cells 48 h after irradiation.

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(b)