Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2016, Article ID 8212063, 10 pages
http://dx.doi.org/10.1155/2016/8212063
Review Article

Relation between Age-Related Macular Degeneration and Cardiovascular Events and Mortality: A Systematic Review and Meta-Analysis

Department of Cardiology, The Second Affiliated Hospital and Yuying Children’s Hospital, Wenzhou Medical University, Xueyuanxi Road, No. 109, Wenzhou, Zhejiang 325000, China

Received 20 May 2016; Revised 27 September 2016; Accepted 14 November 2016

Academic Editor: Gui-shuang Ying

Copyright © 2016 Jie Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. Pascolini, S. P. Mariotti, G. P. Pokharel et al., “2002 Global update of available data on visual impairment: a compilation of population-based prevalence studies,” Ophthalmic Epidemiology, vol. 11, no. 2, pp. 67–115, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. N. Congdon, B. O'Colmain, C. C. Klaver et al., “Causes and prevalence of visual impairment among adults in the United States,” Archives of ophthalmology, vol. 122, no. 4, pp. 477–485, 2004. View at Publisher · View at Google Scholar
  3. R. D. Jager, W. F. Mieler, and J. W. Miller, “Age-related macular degeneration,” New England Journal of Medicine, vol. 358, no. 24, pp. 2606–2617, 2008. View at Publisher · View at Google Scholar
  4. J. Z. Nowak, “Age-related macular degeneration (AMD): pathogenesis and therapy,” Pharmacological Reports, vol. 58, no. 3, pp. 353–363, 2006. View at Google Scholar · View at Scopus
  5. R. Klein, T. Peto, A. Bird, and M. R. Vannewkirk, “The epidemiology of age-related macular degeneration,” American Journal of Ophthalmology, vol. 137, no. 3, pp. 486–495, 2004. View at Publisher · View at Google Scholar · View at Scopus
  6. S. L. Alexander, W. T. Linde-Zwirble, W. Werther et al., “Annual rates of arterial thromboembolic events in medicare neovascular age-related macular degeneration patients,” Ophthalmology, vol. 114, no. 12, pp. 2174–2178, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. T. Y. Wong, G. Tikellis, C. Sun, R. Klein, D. J. Couper, and A. R. Sharrett, “Age-related macular degeneration and risk of coronary heart disease: the Atherosclerosis Risk in Communities Study,” Ophthalmology, vol. 114, no. 1, pp. 86–91, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. T. Y. Wong, R. Klein, C. Sun et al., “Age-related macular degeneration and risk for stroke,” Annals of Internal Medicine, vol. 145, no. 2, pp. 98–106, 2006. View at Publisher · View at Google Scholar · View at Scopus
  9. R. G. Wieberdink, L. Ho, M. K. Ikram et al., “Age-related macular degeneration and the risk of stroke: The Rotterdam Study,” Stroke, vol. 42, no. 8, pp. 2138–2142, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. J. Wu, M. Uchino, S. M. Sastry, and D. A. Schaumberg, “Age-related macular degeneration and the incidence of cardiovascular disease: a systematic review and meta-analysis,” PLoS ONE, vol. 9, no. 3, Article ID e89600, 2014. View at Publisher · View at Google Scholar · View at Scopus
  11. L. A. Stewart, M. Clarke, M. Rovers et al., “Preferred reporting items for systematic review and meta-analyses of individual,” The Journal of the American Medical Association, vol. 313, no. 16, pp. 1657–1665, 2015. View at Publisher · View at Google Scholar
  12. J. Zhang and K. F. Yu, “What's the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes,” The Journal of the American Medical Association, vol. 280, no. 19, pp. 1690–1691, 1998. View at Publisher · View at Google Scholar · View at Scopus
  13. R. DerSimonian and N. Laird, “Meta-analysis in clinical trials revisited,” Contemporary Clinical Trials, vol. 45, pp. 139–145, 2015. View at Publisher · View at Google Scholar
  14. P. H. Borger, R. van Leeuwen, C. A. A. Hulsman et al., “Is there a direct association between age-related eye diseases and mortality? The Rotterdam Study,” Ophthalmology, vol. 110, no. 7, pp. 1292–1296, 2003. View at Publisher · View at Google Scholar · View at Scopus
  15. H. Buch, T. Vinding, M. La Cour, G. B. Jensen, J. U. Prause, and N. V. Nielsen, “Age-related maculopathy: a risk indicator for poorer survival in women: The Copenhagen City Eye Study,” Ophthalmology, vol. 112, no. 2, pp. 305–312, 2005. View at Publisher · View at Google Scholar · View at Scopus
  16. T. E. Clemons, N. Kurinij, R. D. Sperduto, and AREDS Research Group, “Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the age-related eye disease study: AREDS report No. 13,” Archives of Ophthalmology, vol. 122, no. 5, pp. 716–726, 2004. View at Publisher · View at Google Scholar
  17. S. Cugati, R. G. Cumming, W. Smith, G. Burlutsky, P. Mitchell, and J. J. Wang, “Visual impairment, age-related macular degeneration, cataract, and long-term mortality: the blue mountains eye study,” Archives of Ophthalmology, vol. 125, no. 7, pp. 917–924, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. Y. Duan, J. Mo, R. Klein et al., “Age-related macular degeneration is associated with incident myocardial infarction among elderly Americans,” Ophthalmology, vol. 114, no. 4, pp. 732–737, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. A. B. Fernandez, T. Y. Wong, R. Klein et al., “Age-related macular degeneration and incident cardiovascular disease: the Multi-Ethnic study of atherosclerosis,” Ophthalmology, vol. 119, no. 4, pp. 765–770, 2012. View at Publisher · View at Google Scholar · View at Scopus
  20. D. E. Fisher, F. Jonasson, G. Eiriksdottir et al., “Age-related macular degeneration and mortality in community-dwelling elders: the age, gene/environment susceptibility reykjavik study,” Ophthalmology, vol. 122, no. 2, pp. 382–390, 2015. View at Publisher · View at Google Scholar · View at Scopus
  21. S. Golan, V. Shalev, M. Goldstein, G. Treister, G. Chodick, and A. Loewenstein, “The rate of myocardial infarction events among patients with age-related macular degeneration: a population-based study,” Graefe's Archive for Clinical and Experimental Ophthalmology, vol. 249, no. 2, pp. 179–182, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. C.-C. Hu, J.-D. Ho, and H.-C. Lin, “Neovascular age-related macular degeneration and the risk of stroke: a 5-year population-based follow-up study,” Stroke, vol. 41, no. 4, pp. 613–617, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. M. K. Ikram, P. Mitchell, R. Klein, A. R. Sharrett, D. J. Couper, and T. Y. Wong, “Age-related macular degeneration and long-term risk of stroke subtypes,” Stroke, vol. 43, no. 6, pp. 1681–1683, 2012. View at Publisher · View at Google Scholar · View at Scopus
  24. M. D. Knudtson, B. E. K. Klein, and R. Klein, “Age-related eye disease, visual impairment, and survival: the beaver dam eye study,” Archives of Ophthalmology, vol. 124, no. 2, pp. 243–249, 2006. View at Publisher · View at Google Scholar · View at Scopus
  25. D. Liao, J. Mo, Y. Duan et al., “Is age-related macular degeneration associated with stroke among elderly Americans?” The Open Ophthalmology Journal, vol. 2, no. 1, pp. 37–42, 2008. View at Publisher · View at Google Scholar
  26. B.-A. Nguyen-Khoa, E. L. Goehring Jr., W. Werther, E. W. Gower, D. V. Do, and J. K. Jones, “Hospitalized cardiovascular diseases in neovascular age-related macular degeneration,” Archives of Ophthalmology, vol. 126, no. 9, pp. 1280–1286, 2008. View at Publisher · View at Google Scholar · View at Scopus
  27. K. L. Pedula, A. L. Coleman, F. Yu et al., “Age-related macular degeneration and mortality in older women: the study of osteoporotic fractures,” Journal of the American Geriatrics Society, vol. 63, no. 5, pp. 910–917, 2015. View at Publisher · View at Google Scholar · View at Scopus
  28. C. Sun, R. Klein, and T. Y. Wong, “Age-related macular degeneration and risk of coronary heart disease and stroke: The Cardiovascular Health Study,” Ophthalmology, vol. 116, no. 10, pp. 1913–1919, 2009. View at Publisher · View at Google Scholar · View at Scopus
  29. J. S. L. Tan, J. J. Wang, G. Liew, E. Rochtchina, and P. Mitchell, “Age-related macular degeneration and mortality from cardiovascular disease or stroke,” The British Journal of Ophthalmology, vol. 92, no. 4, pp. 509–512, 2008. View at Publisher · View at Google Scholar · View at Scopus
  30. R. Chou, T. Dana, and C. Bougatsos, “Screening older adults for impaired visual acuity: a review of the evidence for the U.S. Preventive Services Task Force,” Annals of Internal Medicine, vol. 151, no. 1, pp. 44–58, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. J. Kulmala, P. Era, O. Pärssinen et al., “Lowered vision as a risk factor for injurious accidents in older people,” Aging Clinical and Experimental Research, vol. 20, no. 1, pp. 25–30, 2008. View at Publisher · View at Google Scholar · View at Scopus
  32. F. G. Holz, S. Schmitz-Valckenberg, and M. Fleckenstein, “Recent developments in the treatment of age-related macular degeneration,” The Journal of Clinical Investigation, vol. 124, no. 4, pp. 1430–1438, 2014. View at Publisher · View at Google Scholar · View at Scopus
  33. S. D. Solomon, K. Lindsley, S. S. Vedula, M. G. Krzystolik, and B. S. Hawkins, “Anti-vascular endothelial growth factor for neovascular age-related macular degeneration,” The Cochrane Database of Systematic Reviews, vol. 8, Article ID CD005139, 2014. View at Google Scholar · View at Scopus