Rationale for the Successful Management of EDTA Chelation Therapy in Human Burden by Toxic Metals

Table 1

Target organs/apparatus, sources, and toxic levels for each toxic metal are reported.

	Main target organs or apparatus									Main assimilation way	Toxic levels; µg/g creatinine
	Kidney	SNC	Liver	Gastrointestinal system	Respiratory system	Skin	Cardiovascular/hematopoietic system	Oral/nasal mucosa	Musculoskeletal system	Ingestion (I); Inhalation (IH); Dermal absorption (DA)
Aluminum		x			x				x	I, IH	35,00
Antimony		x		x	x	x	x		x	I, IH, DA	0,30
Arsenic		x	x	x	x	x	x			I, IH	108,00
Barium		x		x	x		x		x	I, IH	7,00
Beryllium	x		x		x	x				I, IH	1,00
Bismuth	x	x	x		x	x		x	x	I, IH, DA	10,00
Cadmium	x	x	x	x	x		x		x	I, IH	0,80
Cesium	x	x	x	x	x	x	x			I, IH, DA	9,00
Gadolinium				x	x				x	I	0,30
Lead	x	x		x		x	x		x	I, IH, DA	2,00
Mercury	x	x	x	x	x		x	x		I, IH, DA	3,00
Nickel		x			x	x		x	x	I, IH, DA	10,00
Palladium					x	x				I, DA	0,30
Platinum	x			x		x				IH, DA	1,00
Tellurium				x	x	x		x		I, IH	0,80
Thallium		x		x		x	x			I, IH	0,50
Thorium		x	x		x					I, IH	0,03
Tin		x		x		x				I, IH, DA	9,00
Titanium		x		x	x	x		x		I, IH, DA	15,00
Tungsten			x		x	x				I, IH	0,40
Uranium	x	x	x		x	x			x	I, IH, DA	0,03