Antiobesity and Antidiabetes Effects of a Cudrania tricuspidata Hydrophilic Extract Presenting PTP1B Inhibitory Potential

Figure 5

Effect of CTe on blood glucose and insulin levels in DIO mice. The HFD-fed mice were orally administered CTe (20 or 100 mg/kg) for 3 weeks. (a) The effect of CTe on plasma glucose levels in DIO mice. (b) The area under the plasma glucose concentration-time curve for 2 h () in an OGTT. (c) The effect of CTe on plasma insulin in DIO mice. Sitagliptin was used as a positive control. Data are presented as the mean ± SD for each group (). Statistical significance was determined by Student’s t-test. versus vehicle administered DIO mice.

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