The Compound of Mangiferin-Berberine Salt Has Potent Activities in Modulating Lipid and Glucose Metabolisms in HepG2 Cells

Figure 9

Effects of MB salt/M/B on PEPCK/G6Pase mRNA levels. Cells were treated as in Figure 8. After 24 h of treatment, cell total RNA was extracted for real-time RT-PCR determination of PEPCK/G6Pase mRNA levels, which were normalized to that of GAPDH and plotted as fold of DMSO. Values are mean ± SD of 3 separate experiments; and versus that of DMSO; versus those of M alone or B alone in (b); versus that of MB salt alone in (c).

(a)

(b)

(c)