logo

BioMed Research International

BioMed Research International / 2016 / Article / Fig 3

Research Article

Tricholoma matsutake Aqueous Extract Induces Hepatocellular Carcinoma Cell Apoptosis via Caspase-Dependent Mitochondrial Pathway

Figure 3

TM caused apoptotic alternations in mitochondrial function. (a) TM caused intracellular ROS accumulation in HepG2 and SMMC-7721 cells analyzing via DCFH-DA staining after 6 h incubation (20x; scale bar: 100 μm) (). (b) TM induced MMP dissipation detecting by JC-1 staining after 6 h incubation (20x; scale bar: 100 μm) (). (c) 24 h TM exposure enhanced the expressions of cleaved-PARP, Bax, and Bad and suppressed the levels of Bcl-2. Quantification data of protein expressions were normalized by corresponding GAPDH and the average fold of band intensity was marked, respectively ().
(a)
(b)
(c)

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.