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BioMed Research International
Volume 2016 (2016), Article ID 9132198, 3 pages
http://dx.doi.org/10.1155/2016/9132198
Clinical Study

How Effective and Safe Is Bronchial Thermoplasty in “Real Life” Asthmatics Compared to Those Enrolled in Randomized Clinical Trials?

1Dipartimento di Biomedicina e Medicina Specialistica, Sezione di Pneumologia, University of Palermo, Palermo, Italy
2Interventional Endoscopic Unit, ARNAS Ospedale Civico Di Cristina Benfratelli, Palermo, Italy
3Pulmonology Unit, Department of Cardiology, Thoracic and Vascular Surgery and Critical Care Medicine, Azienda Ospedaliera ASMN, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia, Italy

Received 20 June 2016; Accepted 24 August 2016

Academic Editor: Hiroto Matsuse

Copyright © 2016 Rita Arrigo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Bousquet, E. Mantzouranis, A. A. Cruz et al., “Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma,” Journal of Allergy and Clinical Immunology, vol. 126, no. 5, pp. 926–938, 2010. View at Publisher · View at Google Scholar · View at Scopus
  2. Global Strategy for Asthma Management and Prevention, 2016, http://ginasthma.org/.
  3. M. Castro, A. I. Musani, M. L. Mayse, and N. S. Shargill, “Bronchial thermoplasty: a novel technique in the treatment of severe asthma,” Therapeutic Advances in Respiratory Disease, vol. 4, no. 2, pp. 101–116, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Pretolani, M.-C. Dombret, G. Thabut et al., “Reduction of airway smooth muscle mass by bronchial thermoplasty in patients with severe asthma,” American Journal of Respiratory and Critical Care Medicine, vol. 190, no. 12, pp. 1452–1454, 2014. View at Publisher · View at Google Scholar · View at Scopus
  5. D. C. Doeing, A. K. Mahajan, S. R. White, E. T. Naureckas, J. A. Krishnan, and D. K. Hogarth, “Safety and feasibility of bronchial thermoplasty in asthma patients with very severe fixed airflow obstruction: a case series,” Journal of Asthma, vol. 50, no. 2, pp. 215–218, 2013. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Bicknell, R. Chaudhuri, N. Lee et al., “Effectiveness of bronchial thermoplasty in severe asthma in ‘real life’ patients compared with those recruited to clinical trials in the same centre,” Therapeutic Advances in Respiratory Disease, vol. 9, no. 6, pp. 267–271, 2015. View at Publisher · View at Google Scholar · View at Scopus
  7. K. F. Chung, S. E. Wenzel, J. L. Brozek et al., “International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma,” European Respiratory Journal, vol. 43, no. 2, pp. 343–373, 2014. View at Publisher · View at Google Scholar · View at Scopus
  8. N. Facciolongo, F. Menzella, M. Lusuardi et al., “Recurrent lung atelectasis from fibrin plugs as a very early complication of bronchial thermoplasty: a case report,” Multidisciplinary Respiratory Medicine, vol. 10, no. 1, article 9, 2015. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Castro, A. S. Rubin, M. Laviolette et al., “Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized, double-blind, sham-controlled clinical trial,” American Journal of Respiratory and Critical Care Medicine, vol. 181, no. 2, pp. 116–124, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. M. J. Cangelosi, J. D. Ortendahl, L. M. Meckley et al., “Cost-effectiveness of bronchial thermoplasty in commercially-insured patients with poorly controlled, severe, persistent asthma,” Expert Review of Pharmacoeconomics and Outcomes Research, vol. 15, no. 2, pp. 357–364, 2015. View at Publisher · View at Google Scholar · View at Scopus