Therapeutic Effects of CUR-Activated Human Umbilical Cord Mesenchymal Stem Cells on 1-Methyl-4-phenylpyridine-Induced Parkinson’s Disease Cell Model

Figure 2

Expressions of bcl-2 and caspase detected by RT-PCR: the bcl-2 mRNA expression was elevated (a, b) and caspase-3 mRNA expression was reduced (c, d) after the PD cell model was treated with CM-CUR, CM-MSC, and CUR for 48 h and showed statistically significant differences compared with the model group (). The effect was still the strongest in the CM-CUR group (), which did not show any significant difference compared with the control group. The mRNA expressions in the CM-MSC and CUR groups were lower than the control group (), while the difference between the CM-MSC and CUR groups was not significant.

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