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BioMed Research International
Volume 2016, Article ID 9241278, 7 pages
http://dx.doi.org/10.1155/2016/9241278
Research Article

Association of Microalbuminuria with Metabolic Syndrome among Aged Population

1Health Management Center, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China
2Department of Burn and Plastic Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China

Received 31 January 2016; Revised 29 March 2016; Accepted 5 April 2016

Academic Editor: Francesco Perticone

Copyright © 2016 Xiao-Hong Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. The impact of the various components of metabolic syndrome (MetS) on chronic kidney disease has been conflicting. We aim to investigate the association between MetS and microalbuminuria and identify the major contributing components of MetS that result in microalbuminuria in the Chinese aged population. Methods. A total of 674 adults aged 55–98 years (males: 266; mean age: years) were studied. MetS was defined by the 2004 Chinese Diabetes Society criteria and microalbuminuria by urine albumin-creatinine ratio (UACR) ≥3 mg/mmoL. Results. The prevalence of microalbuminuria was gradually increased with increasing number of MetS components (). In multivariate regression, after adjusting for age and sex, MetS was the strongest correlate of microalbuminuria (OR = 1.781, 95% CI = 1.226–2.587; ) followed by the fasting plasma glucose (FPG) (OR = 1.217, 95% CI = 1.044–1.092; ), systolic blood pressure (SBP) (OR = 1.011, 95% CI = 1.107–1.338; ), and high-density lipoprotein cholesterol (HDL-C) (OR = 0.576, 95% CI = 0.348–0.953; ). Conclusions. MetS is independently associated with microalbuminuria in the Chinese aged population. Elevated FPG is the most predominant component of metabolic syndrome associated with microalbuminuria followed by elevated SBP and reduced HDL-C.