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BioMed Research International
Volume 2016 (2016), Article ID 9367464, 13 pages
http://dx.doi.org/10.1155/2016/9367464
Review Article

Venovenous Extracorporeal Membrane Oxygenation in Intractable Pulmonary Insufficiency: Practical Issues and Future Directions

1Department of Cardiology, Maastricht University Medical Center, 6202 AZ Maastricht, Netherlands
2Department of Intensive Care, Maastricht University Medical Center, 6202 AZ Maastricht, Netherlands
3Department of Cardiothoracic Surgery, Maastricht University Medical Center, 6202 AZ Maastricht, Netherlands
4Department of Anesthesiology, Maastricht University Medical Center, 6202 AZ Maastricht, Netherlands

Received 6 January 2016; Accepted 3 March 2016

Academic Editor: Boris Jung

Copyright © 2016 T. S. R. Delnoij et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Venovenous extracorporeal membrane oxygenation (vv-ECMO) is a highly invasive method for organ support that is gaining in popularity due to recent technical advances and its successful application in the recent H1N1 epidemic. Although running a vv-ECMO program is potentially feasible for many hospitals, there are many theoretical concepts and practical issues that merit attention and require expertise. In this review, we focus on indications for vv-ECMO, components of the circuit, and management of patients on vv-ECMO. Concepts regarding oxygenation and decarboxylation and how they can be influenced are discussed. Day-to-day management, weaning, and most frequent complications are covered in light of the recent literature.