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BioMed Research International
Volume 2016, Article ID 9367464, 13 pages
http://dx.doi.org/10.1155/2016/9367464
Review Article

Venovenous Extracorporeal Membrane Oxygenation in Intractable Pulmonary Insufficiency: Practical Issues and Future Directions

1Department of Cardiology, Maastricht University Medical Center, 6202 AZ Maastricht, Netherlands
2Department of Intensive Care, Maastricht University Medical Center, 6202 AZ Maastricht, Netherlands
3Department of Cardiothoracic Surgery, Maastricht University Medical Center, 6202 AZ Maastricht, Netherlands
4Department of Anesthesiology, Maastricht University Medical Center, 6202 AZ Maastricht, Netherlands

Received 6 January 2016; Accepted 3 March 2016

Academic Editor: Boris Jung

Copyright © 2016 T. S. R. Delnoij et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. L. Paden, P. T. Rycus, and R. R. Thiagarajan, “Update and outcomes in extracorporeal life support,” Seminars in Perinatology, vol. 38, no. 2, pp. 65–70, 2014. View at Publisher · View at Google Scholar · View at Scopus
  2. M. A. Schechter, A. M. Ganapathi, B. R. Englum et al., “Spontaneously breathing extracorporeal membrane oxygenation support provides the optimal bridge to lung transplantation,” Transplantation, 2016. View at Publisher · View at Google Scholar
  3. J. F. Murray, M. A. Matthay, J. M. Luce, and M. R. Flick, “An expanded definition of the adult respiratory distress syndrome,” American Review of Respiratory Disease, vol. 138, no. 3, pp. 720–723, 1988. View at Publisher · View at Google Scholar · View at Scopus
  4. K. N. Kangelaris, C. S. Calfee, A. K. May, H. Zhuo, M. A. Matthay, and L. B. Ware, “Is there still a role for the lung injury score in the era of the Berlin definition ARDS?” Annals of Intensive Care, vol. 4, article 4, 2014. View at Publisher · View at Google Scholar · View at Scopus
  5. C. Guérin, J. Reignier, J. Richard et al., “Prone positioning in severe acute respiratory distress syndrome,” The New England Journal of Medicine, vol. 368, no. 23, pp. 2159–2168, 2013. View at Publisher · View at Google Scholar
  6. S. L. Hu, H. L. He, C. Pan et al., “The effect of prone positioning on mortality in patients with acute respiratory distress syndrome: a meta-analysis of randomized controlled trials,” Critical Care, vol. 18, no. 3, article R109, 2014. View at Publisher · View at Google Scholar · View at Scopus
  7. J. M. Lee, W. Bae, Y. J. Lee, and Y.-J. Cho, “The efficacy and safety of prone positional ventilation in acute respiratory distress syndrome: updated study-level meta-analysis of 11 randomized controlled trials,” Critical Care Medicine, vol. 42, no. 5, pp. 1252–1262, 2014. View at Publisher · View at Google Scholar · View at Scopus
  8. A. Afshari, J. Brok, A. M. Møller, and J. Wetterslev, “Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) and acute lung injury in children and adults,” Cochrane Database of Systematic Reviews, vol. 7, Article ID CD002787, 2010. View at Google Scholar · View at Scopus
  9. X.-L. Gu, G.-N. Wu, Y.-W. Yao, D.-H. Shi, and Y. Song, “Is high-frequency oscillatory ventilation more effective and safer than conventional protective ventilation in adult acute respiratory distress syndrome patients? A meta-analysis of randomized controlled trials,” Critical Care, vol. 18, no. 3, article R111, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. R. Lall, P. Hamilton, D. Young et al., “A randomised controlled trial and cost-effectiveness analysis of high-frequency oscillatory ventilation against conventional artificial ventilation for adults with acute respiratory distress syndrome. The OSCAR (OSCillation in ARDS) study,” Health Technology Assessment, vol. 19, no. 23, pp. 1–177, 2015. View at Publisher · View at Google Scholar
  11. C. Hodgson, J. L. Keating, A. E. Holland et al., “Recruitment manoeuvres for adults with acute lung injury receiving mechanical ventilation,” Cochrane Database of Systematic Reviews, no. 2, Article ID CD006667, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. G. J. Peek, M. Mugford, R. Tiruvoipati et al., “Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial,” The Lancet, vol. 374, no. 9698, pp. 1351–1363, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. A. R. Davies, D. Jones, M. Bailey et al., “Extracorporeal membrane oxygenation for 2009 influenza A(H1N1) acute respiratory distress syndrome,” The Journal of the American Medical Association, vol. 302, no. 17, pp. 1888–1895, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. N. Patroniti, A. Zangrillo, F. Pappalardo et al., “The Italian ECMO network experience during the 2009 influenza A(H1N1) pandemic: preparation for severe respiratory emergency outbreaks,” Intensive Care Medicine, vol. 37, no. 9, pp. 1447–1457, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. T. Pham, A. Combes, H. Rozé et al., “Extracorporeal membrane oxygenation for pandemic influenza A(H1N1)-induced acute respiratory distress syndrome: a cohort study and propensity-matched analysis,” American Journal of Respiratory and Critical Care Medicine, vol. 187, no. 3, pp. 276–285, 2013. View at Publisher · View at Google Scholar
  16. L.-C. Chiu, F.-C. Tsai, H.-C. Hu et al., “Survival predictors in acute respiratory distress syndrome with extracorporeal membrane oxygenation,” Annals of Thoracic Surgery, vol. 99, no. 1, pp. 243–250, 2015. View at Publisher · View at Google Scholar · View at Scopus
  17. A. Roch, S. Hraiech, E. Masson et al., “Outcome of acute respiratory distress syndrome patients treated with extracorporeal membrane oxygenation and brought to a referral center,” Intensive Care Medicine, vol. 40, no. 1, pp. 74–83, 2014. View at Publisher · View at Google Scholar · View at Scopus
  18. M. Schmidt, M. Bailey, J. Sheldrake et al., “Predicting survival after extracorporeal membrane oxygenation for severe acute respiratory failure. The Respiratory Extracorporeal Membrane Oxygenation Survival Prediction (RESP) score,” American Journal of Respiratory and Critical Care Medicine, vol. 189, no. 11, pp. 1374–1382, 2014. View at Publisher · View at Google Scholar
  19. M. Schmidt, E. Zogheib, H. Rozé et al., “The PRESERVE mortality risk score and analysis of long-term outcomes after extracorporeal membrane oxygenation for severe acute respiratory distress syndrome,” Intensive Care Medicine, vol. 39, no. 10, pp. 1704–1713, 2013. View at Publisher · View at Google Scholar · View at Scopus
  20. E. Fosse, O. Moen, E. Johnson et al., “Reduced complement and granulocyte activation with heparin-coated cardiopulmonary bypass,” The Annals of Thoracic Surgery, vol. 58, no. 2, pp. 472–477, 1994. View at Publisher · View at Google Scholar · View at Scopus
  21. F. B. Plotz, W. Van Oeveren, R. H. Bartlett, and C. R. H. Wildevuur, “Blood activation during neonatal extracorporeal life support,” Journal of Thoracic and Cardiovascular Surgery, vol. 105, no. 5, pp. 823–832, 1993. View at Google Scholar · View at Scopus
  22. M. Sobel, P. M. McNeill, P. L. Carlson et al., “Heparin inhibition of von Willebrand factor-dependent platelet function in vitro and in vivo,” Journal of Clinical Investigation, vol. 87, no. 5, pp. 1787–1793, 1991. View at Publisher · View at Google Scholar · View at Scopus
  23. P. W. Weerwind, J. G. Maessen, L. J. H. van Tits et al., “Influence of Duraflo II heparin-treated extracorporeal circuits on the systemic inflammatory response in patients having coronary bypass,” The Journal of Thoracic and Cardiovascular Surgery, vol. 110, no. 6, pp. 1633–1641, 1995. View at Publisher · View at Google Scholar · View at Scopus
  24. M. R. Hemmila, S. A. Rowe, T. N. Boules et al., “Extracorporeal life support for severe acute respiratory distress syndrome in adults,” Annals of Surgery, vol. 240, no. 4, pp. 595–607, 2004. View at Publisher · View at Google Scholar · View at Scopus
  25. T. Müller, A. Philipp, A. Luchner et al., “A new miniaturized system for extracorporeal membrane oxygenation in adult respiratory failure,” Critical Care, vol. 13, no. 6, article R205, 2009. View at Publisher · View at Google Scholar · View at Scopus
  26. C. A. Bermudez, R. V. Rocha, P. L. Sappington, Y. Toyoda, H. N. Murray, and A. J. Boujoukos, “Initial experience with single cannulation for venovenous extracorporeal oxygenation in adults,” Annals of Thoracic Surgery, vol. 90, no. 3, pp. 991–995, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. J. Javidfar, D. Wang, J. B. Zwischenberger et al., “Insertion of Bicaval Dual Lumen extracorporeal membrane oxygenation catheter with image guidance,” ASAIO Journal, vol. 57, no. 3, pp. 203–205, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. J. D. Fortenberry, R. Pettignano, and F. Dykes, “Principles and practice of venovenous ECMO,” in ECMO Extracorporeal Cardiopulmonary Support in Critical Care, K. Van Meurs, K. P. Lally, G. Peek, and J. B. Zwischenberger, Eds., Extracorporeal Life Support Organization, Ann Arbor, Mich, USA, 2000. View at Google Scholar
  29. D. Clements, J. Primmer, P. Ryman, B. Marr, B. Searles, and E. Darling, “Measurements of recirculation during neonatal veno-venous extracorporeal membrane oxygenation: clinical application of the ultrasound dilution technique,” Journal of Extra Corporeal Technology, vol. 40, no. 3, pp. 184–187, 2008. View at Google Scholar · View at Scopus
  30. D. Abrams, M. Bacchetta, and D. Brodie, “Recirculation in venovenous extracorporeal membrane oxygenation,” ASAIO Journal, vol. 61, no. 2, pp. 115–121, 2015. View at Publisher · View at Google Scholar · View at Scopus
  31. M. Schmidt, G. Tachon, C. Devilliers et al., “Blood oxygenation and decarboxylation determinants during venovenous ECMO for respiratory failure in adults,” Intensive Care Medicine, vol. 39, no. 5, pp. 838–846, 2013. View at Publisher · View at Google Scholar · View at Scopus
  32. E. P. J. Körver, Y. M. Ganushchak, A. P. Simons, D. W. Donker, J. G. Maessen, and P. W. Weerwind, “Quantification of recirculation as an adjuvant to transthoracic echocardiography for optimization of dual-lumen extracorporeal life support,” Intensive Care Medicine, vol. 38, no. 5, pp. 906–909, 2012. View at Publisher · View at Google Scholar · View at Scopus
  33. A. F. van Heijst, F. H. van Der Staak, A. F. De Haan et al., “Recirculation in double lumen catheter veno-venous extracorporeal membrane oxygenation measured by an ultrasound dilution technique,” ASAIO Journal, vol. 47, no. 4, pp. 372–376, 2001. View at Publisher · View at Google Scholar · View at Scopus
  34. R. H. Bartlett, “Physiology of extracorporeal life support,” in ECMO Extracorporeal Cardiopulmonary Support in Critical Care, J. B. Zwischenberger and R. H. Bartlett, Eds., Extracorporeal Life Support Organization, Ann Arbor, Mich, USA, 2000. View at Google Scholar
  35. M. Lamy, R. C. Eberhart, R. J. Fallat, H. P. Dietrich, J. Ratliff, and J. D. Hill, “Effects of extracorporeal membrane oxygenation (ECMO) on pulmonary hemodynamics, gas exchange and prognose,” Transactions of the American Society for Artificial Internal Organs, vol. 21, pp. 188–198, 1975. View at Google Scholar · View at Scopus
  36. T. Bein, F. Weber, A. Philipp et al., “A new pumpless extracorporeal interventional lung assist in critical hypoxemia/hypercapnia,” Critical Care Medicine, vol. 34, no. 5, pp. 1372–1377, 2006. View at Publisher · View at Google Scholar · View at Scopus
  37. P. Terragni, G. Maiolo, and V. M. Ranieri, “Role and potentials of low-flow CO2 removal system in mechanical ventilation,” Current Opinion in Critical Care, vol. 18, no. 1, pp. 93–98, 2012. View at Publisher · View at Google Scholar · View at Scopus
  38. D. Sidebotham, S. J. Allen, A. McGeorge, N. Ibbott, and T. Willcox, “Venovenous extracorporeal membrane oxygenation in adults: practical aspects of circuits, cannulae, and procedures,” Journal of Cardiothoracic and Vascular Anesthesia, vol. 26, no. 5, pp. 893–909, 2012. View at Publisher · View at Google Scholar · View at Scopus
  39. D. Brodie and M. Bacchetta, “Extracorporeal membrane oxygenation for ARDS in adults,” New England Journal of Medicine, vol. 365, no. 20, pp. 1905–1914, 2011. View at Publisher · View at Google Scholar · View at Scopus
  40. A. Kimmoun, F. Vanhuyse, and B. Levy, “Improving blood oxygenation during venovenous ECMO for ARDS,” Intensive Care Medicine, vol. 39, no. 6, pp. 1161–1162, 2013. View at Publisher · View at Google Scholar · View at Scopus
  41. F. Pappalardo, A. Zangrillo, M. Pieri et al., “Esmolol administration in patients with VV ECMO: why not?” Journal of Cardiothoracic and Vascular Anesthesia, vol. 27, no. 4, p. e40, 2013. View at Publisher · View at Google Scholar · View at Scopus
  42. A. Morelli, C. Ertmer, M. Westphal et al., “Effect of heart rate control with esmolol on hemodynamic and clinical outcomes in patients with septic shock: a randomized clinical trial,” The Journal of the American Medical Association, vol. 310, no. 16, pp. 1683–1691, 2013. View at Publisher · View at Google Scholar · View at Scopus
  43. R. G. Brower, M. A. Matthay, A. Morris, D. Schoenfeld, B. T. Thompson, and A. Wheeler, “Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome,” New England Journal of Medicine, vol. 342, no. 18, pp. 1301–1308, 2000. View at Publisher · View at Google Scholar · View at Scopus
  44. J. D. Marhong, L. Munshi, M. Detsky, T. Telesnicki, and E. Fan, “Mechanical ventilation during extracorporeal life support (ECLS): a systematic review,” Intensive Care Medicine, vol. 41, no. 6, pp. 994–1003, 2015. View at Publisher · View at Google Scholar · View at Scopus
  45. B. Lachmann, “Open up the lung and keep the lung open,” Intensive Care Medicine, vol. 18, no. 6, pp. 319–321, 1992. View at Publisher · View at Google Scholar · View at Scopus
  46. M. Schmidt, C. Stewart, M. Bailey et al., “Mechanical ventilation management during extracorporeal membrane oxygenation for acute respiratory distress syndrome: a retrospective international multicenter study,” Critical Care Medicine, vol. 43, no. 3, pp. 654–664, 2015. View at Publisher · View at Google Scholar · View at Scopus
  47. R. E. Culbreth and L. T. Goodfellow, “Complications of prone positioning during extracorporeal membrane oxygenation for respiratory failure: a systematic review,” Respiratory Care, vol. 61, no. 2, pp. 249–254, 2016. View at Publisher · View at Google Scholar
  48. A. Kimmoun, S. Roche, C. Bridey et al., “Prolonged prone positioning under VV-ECMO is safe and improves oxygenation and respiratory compliance,” Annals of Intensive Care, vol. 5, no. 1, article 35, 2015. View at Publisher · View at Google Scholar · View at Scopus
  49. A. Nieszkowska, A. Combes, C.-E. Luyt et al., “Impact of tracheotomy on sedative administration, sedation level, and comfort of mechanically ventilated intensive care unit patients,” Critical Care Medicine, vol. 33, no. 11, pp. 2527–2533, 2005. View at Publisher · View at Google Scholar · View at Scopus
  50. S. Braune, S. Kienast, J. Hadem et al., “Safety of percutaneous dilatational tracheostomy in patients on extracorporeal lung support,” Intensive Care Medicine, vol. 39, no. 10, pp. 1792–1799, 2013. View at Publisher · View at Google Scholar · View at Scopus
  51. H. P. Wiedemann, A. P. Wheeler, G. R. Bernard et al., “Comparison of two fluid-management strategies in acute lung injury,” The New England Journal of Medicine, vol. 354, no. 24, pp. 2564–2575, 2006. View at Publisher · View at Google Scholar · View at Scopus
  52. C.-Y. Lin, Y.-C. Chen, F.-C. Tsai et al., “RIFLE classification is predictive of short-term prognosis in critically ill patients with acute renal failure supported by extracorporeal membrane oxygenation,” Nephrology Dialysis Transplantation, vol. 21, no. 10, pp. 2867–2873, 2006. View at Publisher · View at Google Scholar · View at Scopus
  53. H. Chen, R.-G. Yu, N.-N. Yin, and J.-X. Zhou, “Combination of extracorporeal membrane oxygenation and continuous renal replacement therapy in critically ill patients: a systematic review,” Critical Care, vol. 18, no. 6, article 675, 2014. View at Publisher · View at Google Scholar · View at Scopus
  54. M. T. Voelker, T. Busch, S. Bercker, F. Fichtner, U. X. Kaisers, and S. Laudi, “Restrictive transfusion practice during extracorporeal membrane oxygenation therapy for severe acute respiratory distress syndrome,” Artificial Organs, vol. 39, no. 4, pp. 374–378, 2015. View at Publisher · View at Google Scholar · View at Scopus
  55. C. L. Agerstrand, K. M. Burkart, D. C. Abrams, M. D. Bacchetta, and D. Brodie, “Blood conservation in extracorporeal membrane oxygenation for acute respiratory distress syndrome,” Annals of Thoracic Surgery, vol. 99, no. 2, pp. 590–595, 2015. View at Publisher · View at Google Scholar · View at Scopus
  56. A. A. Harthan, K. W. Buckley, M. L. Heger, R. S. Fortuna, and K. Mays, “Medication adsorption into contemporary extracorporeal membrane oxygenator circuits,” The Journal of Pediatric Pharmacology and Therapeutics, vol. 19, no. 4, pp. 288–295, 2014. View at Publisher · View at Google Scholar
  57. D. Abrams, J. Javidfar, E. Farrand et al., “Early mobilization of patients receiving extracorporeal membrane oxygenation: a retrospective cohort study,” Critical Care, vol. 18, no. 1, article R38, 2014. View at Publisher · View at Google Scholar · View at Scopus
  58. Y. Ko, Y. H. Cho, Y. H. Park et al., “Feasibility and safety of early physical therapy and active mobilization for patients on extracorporeal membrane oxygenation,” ASAIO Journal, vol. 61, no. 5, pp. 564–568, 2015. View at Publisher · View at Google Scholar
  59. M. L. Paden, S. A. Conrad, P. T. Rycus, and R. R. Thiagarajan, “Extracorporeal life support organization registry report 2012,” ASAIO Journal, vol. 59, no. 3, pp. 202–210, 2013. View at Publisher · View at Google Scholar · View at Scopus
  60. S. Atallah, M. Liebl, K. Fitousis, F. Bostan, and F. Masud, “Evaluation of the activated clotting time and activated partial thromboplastin time for the monitoring of heparin in adult extracorporeal membrane oxygenation patients,” Perfusion, vol. 29, no. 5, pp. 456–461, 2014. View at Publisher · View at Google Scholar · View at Scopus
  61. T. M. Maul, E. L. Wolff, B. A. Kuch, A. Rosendorff, V. O. Morell, and P. D. Wearden, “Activated partial thromboplastin time is a better trending tool in pediatric extracorporeal membrane oxygenation,” Pediatric Critical Care Medicine, vol. 13, no. 6, pp. e363–e371, 2012. View at Publisher · View at Google Scholar · View at Scopus
  62. T. Bein, M. Zimmermann, A. Philipp et al., “Addition of acetylsalicylic acid to heparin for anticoagulation management during pumpless extracorporeal lung assist,” ASAIO Journal, vol. 57, no. 3, pp. 164–168, 2011. View at Publisher · View at Google Scholar · View at Scopus
  63. A. Phillip, T. Müller, T. Bein et al., “Inhibition of thrombocyte aggregation during extracorporeal lung assist: a case report,” Perfusion, vol. 22, no. 4, pp. 293–297, 2007. View at Publisher · View at Google Scholar · View at Scopus
  64. D. Paparella, T. M. Yau, and E. Young, “Cardiopulmonary bypass induced inflammation: pathophysiology and treatment. An update,” European Journal of Cardio-thoracic Surgery, vol. 21, no. 2, pp. 232–244, 2002. View at Publisher · View at Google Scholar · View at Scopus
  65. C. Aubron, A. C. Cheng, D. Pilcher et al., “Infections acquired by adults who receive extracorporeal membrane oxygenation: risk factors and outcome,” Infection Control and Hospital Epidemiology, vol. 34, no. 1, pp. 24–30, 2013. View at Publisher · View at Google Scholar · View at Scopus
  66. H.-Y. Sun, W.-J. Ko, P.-R. Tsai et al., “Infections occurring during extracorporeal membrane oxygenation use in adult patients,” Journal of Thoracic and Cardiovascular Surgery, vol. 140, no. 5, pp. 1125–1132.e2, 2010. View at Publisher · View at Google Scholar · View at Scopus
  67. T. V. Brogan, R. R. Thiagarajan, P. T. Rycus, R. H. Bartlett, and S. L. Bratton, “Extracorporeal membrane oxygenation in adults with severe respiratory failure: a multi-center database,” Intensive Care Medicine, vol. 35, no. 12, pp. 2105–2114, 2009. View at Publisher · View at Google Scholar · View at Scopus
  68. V. Kasirajan, N. G. Smedira, J. F. McCarthy, F. Casselman, N. Boparai, and P. M. McCarthy, “Risk factors for intracranial hemorrhage in adults on extracorporeal membrane oxygenation,” European Journal of Cardio-Thoracic Surgery, vol. 15, no. 4, pp. 508–514, 1999. View at Publisher · View at Google Scholar · View at Scopus
  69. M. Arlt, A. Philipp, S. Voelkel et al., “Extracorporeal membrane oxygenation in severe trauma patients with bleeding shock,” Resuscitation, vol. 81, no. 7, pp. 804–809, 2010. View at Publisher · View at Google Scholar · View at Scopus
  70. C. C. Geelen, E. A. Bouman, P. M. Roekaerts et al., “Mobile extracorporeal membrane oxygenation after traumatic freshwater submersion using bi-caval dual lumen catheter,” Intensive Care Medicine, vol. 37, no. 12, pp. 2054–2055, 2011. View at Publisher · View at Google Scholar · View at Scopus
  71. R. M. Muellenbach, M. Kredel, E. Kunze et al., “Prolonged heparin-free extracorporeal membrane oxygenation in multiple injured acute respiratory distress syndrome patients with traumatic brain injury,” Journal of Trauma and Acute Care Surgery, vol. 72, no. 5, pp. 1444–1447, 2012. View at Publisher · View at Google Scholar · View at Scopus
  72. F. H. J. van der Staak, A. F. J. de Haan, W. B. Geven, and C. Festen, “Surgical repair of congenital diaphragmatic hernia during extracorporeal membrane oxygenation: hemorrhagic complications and the effect of tranexamic acid,” Journal of Pediatric Surgery, vol. 32, no. 4, pp. 594–599, 1997. View at Publisher · View at Google Scholar · View at Scopus
  73. A. P. Simons, Y. M. Ganushchak, S. Teerenstra, D. C. Bergmans, J. G. Maessen, and P. W. Weerwind, “Hypovolemia in extracorporeal life support can lead to arterial gaseous microemboli,” Artificial Organs, vol. 37, no. 3, pp. 276–282, 2013. View at Publisher · View at Google Scholar · View at Scopus
  74. J. B. Zwischenberger, R. E. Cilley, R. B. Hirschl, K. F. Heiss, V. R. Conti, and R. H. Bartlett, “Life-threatening intrathoracic complications during treatment with extracorporeal membrane oxygenation,” Journal of Pediatric Surgery, vol. 23, no. 7, pp. 599–604, 1988. View at Publisher · View at Google Scholar · View at Scopus
  75. T. E. Warkentin, “Laboratory testing for heparin-induced thrombocytopenia,” Journal of Thrombosis and Thrombolysis, vol. 10, supplement 1, pp. S35–S45, 2000. View at Google Scholar · View at Scopus
  76. N. Antier, J. Quenot, J. Doise, R. Noel, E. Demaistre, and H. Devilliers, “Mechanisms and etiologies of thrombocytopenia in the intensive care unit: impact of extensive investigations,” Annals of Intensive Care, vol. 4, no. 1, p. 24, 2014. View at Publisher · View at Google Scholar
  77. T. Kawada, H. Kitagawa, M. Hoson, Y. Okada, and J. Shiomura, “Clinical application of argatroban as an alternative anticoagulant for extracorporeal circulation,” Hematology/Oncology Clinics of North America, vol. 14, no. 2, pp. 445–457, 2000. View at Publisher · View at Google Scholar · View at Scopus
  78. G. Young, K. E. Yonekawa, P. Nakagawa, and D. J. Nugent, “Argatroban as an alternative to heparin in extracorporeal membrane oxygenation circuits,” Perfusion, vol. 19, no. 5, pp. 283–288, 2004. View at Publisher · View at Google Scholar · View at Scopus
  79. A. Koster, Y. Weng, W. Böttcher, T. Gromann, H. Kuppe, and R. Hetzer, “Successful use of bivalirudin as anticoagulant for ECMO in a patient with acute HIT,” Annals of Thoracic Surgery, vol. 83, no. 5, pp. 1865–1867, 2007. View at Publisher · View at Google Scholar · View at Scopus
  80. C. Bauer, Z. Vichova, P. Ffrench et al., “Extracorporeal membrane oxygenation with danaparoid sodium after massive pulmonary embolism,” Anesthesia and Analgesia, vol. 106, no. 4, pp. 1101–1103, 2008. View at Publisher · View at Google Scholar · View at Scopus
  81. S. K. Balasubramanian, R. Tiruvoipati, S. Chatterjee, A. Sosnowski, and R. K. Firmin, “Extracorporeal membrane oxygenation with lepirudin anticoagulation for Wegener's granulomatosis with heparin-induced thrombocytopenia,” ASAIO Journal, vol. 51, no. 4, pp. 477–479, 2005. View at Publisher · View at Google Scholar · View at Scopus
  82. W. E. Dager, R. C. Gosselin, R. Yoshikawa, and J. T. Owings, “Lepirudin in heparin-induced thrombocytopenia and extracorporeal membranous oxygenation,” Annals of Pharmacotherapy, vol. 38, no. 4, pp. 598–601, 2004. View at Publisher · View at Google Scholar · View at Scopus
  83. A. I. Parlar, U. Sayar, D. Cevirme, M. A. Yuruk, and I. Mataraci, “Successful use of fondaparinux in a patient with heparin-induced thrombocytopenia while on extracorporeal membrane oxygenation after mitral valve redo surgery,” International Journal of Artificial Organs, vol. 37, no. 4, pp. 344–347, 2014. View at Publisher · View at Google Scholar · View at Scopus
  84. A. Koster, S. Sänger, R. Hansen et al., “Prevalence and persistence of heparin/platelet factor 4 antibodies in patients with heparin coated and noncoated ventricular assist devices,” ASAIO Journal, vol. 46, no. 3, pp. 319–322, 2000. View at Publisher · View at Google Scholar · View at Scopus
  85. K. Lehle, A. Philipp, O. Gleich et al., “Efficiency in extracorporeal membrane oxygenation—cellular deposits on polymethypentene membranes increase resistance to blood flow and reduce gas exchange capacity,” ASAIO Journal, vol. 54, no. 6, pp. 612–617, 2008. View at Publisher · View at Google Scholar · View at Scopus
  86. C. Dornia, A. Philipp, S. Bauer et al., “D-dimers are a predictor of clot volume inside membrane oxygenators during extracorporeal membrane oxygenation,” Artificial Organs, vol. 39, no. 9, pp. 782–787, 2015. View at Publisher · View at Google Scholar · View at Scopus
  87. M. Lubnow, A. Philipp, C. Dornia et al., “D-dimers as an early marker for oxygenator exchange in extracorporeal membrane oxygenation,” Journal of Critical Care, vol. 29, no. 3, pp. 473.e1–473.e5, 2014. View at Publisher · View at Google Scholar · View at Scopus
  88. U. Beckmann, D. M. Gillies, S. M. Berenholtz, A. W. Wu, and P. Pronovost, “Incidents relating to the intra-hospital transfer of critically ill patients: an analysis of the reports submitted to the Australian Incident Monitoring Study in Intensive Care,” Intensive Care Medicine, vol. 30, no. 8, pp. 1579–1585, 2004. View at Google Scholar · View at Scopus
  89. B. Fanara, C. Manzon, O. Barbot, T. Desmettre, and G. Capellier, “Recommendations for the intra-hospital transport of critically ill patients,” Critical Care, vol. 14, no. 3, article R87, 2010. View at Publisher · View at Google Scholar · View at Scopus
  90. V. Gariboldi, D. Grisoli, A. Tarmiz et al., “Mobile extracorporeal membrane oxygenation unit expands cardiac assist surgical programs,” Annals of Thoracic Surgery, vol. 90, no. 5, pp. 1548–1552, 2010. View at Publisher · View at Google Scholar · View at Scopus
  91. D. Lahner, A. Nikolic, P. Marhofer et al., “Incidence of complications in intrahospital transport of critically ill patients-experience in an Austrian university hospital,” Wiener Klinische Wochenschrift, vol. 119, no. 13-14, pp. 412–416, 2007. View at Publisher · View at Google Scholar · View at Scopus
  92. J. P. N. Papson, K. L. Russell, and D. M. Taylor, “Unexpected events during the intrahospital transport of critically ill patients,” Academic Emergency Medicine, vol. 14, no. 6, pp. 574–577, 2007. View at Publisher · View at Google Scholar · View at Scopus
  93. J. Warren, R. E. Fromm Jr., R. A. Orr, L. C. Rotello, and H. Mathilda Horst, “Guidelines for the inter- and intrahospital transport of critically ill patients,” Critical Care Medicine, vol. 32, no. 1, pp. 256–262, 2004. View at Publisher · View at Google Scholar · View at Scopus
  94. L. M. Broman, B. Holzgraefe, K. Palmér, and B. Frenckner, “The Stockholm experience: interhospital transports on extracorporeal membrane oxygenation,” Critical Care, vol. 19, article 278, 2015. View at Publisher · View at Google Scholar · View at Scopus
  95. C. P. Coppola, M. Tyree, K. Larry, and R. DiGeronimo, “A 22-year experience in global transport extracorporeal membrane oxygenation,” Journal of Pediatric Surgery, vol. 43, no. 1, pp. 46–52, 2008. View at Publisher · View at Google Scholar · View at Scopus
  96. T. S. R. Delnoij, G. Veldhuijzen, U. Strauch et al., “Mobile respiratory rescue support by off-centre initiation of extracorporeal membrane oxygenation,” Perfusion, vol. 30, no. 3, pp. 255–259, 2014. View at Publisher · View at Google Scholar · View at Scopus
  97. D. S. Foley, T. Pranikoff, J. G. Younger et al., “A review of 100 patients transported on extracorporeal life support,” ASAIO Journal, vol. 48, no. 6, pp. 612–619, 2002. View at Publisher · View at Google Scholar · View at Scopus
  98. P. Forrest, J. Ratchford, B. Burns et al., “Retrieval of critically ill adults using extracorporeal membrane oxygenation: an Australian experience,” Intensive Care Medicine, vol. 37, no. 5, pp. 824–830, 2011. View at Publisher · View at Google Scholar · View at Scopus
  99. U. Strauch, D. C. Bergmans, B. Winkens, and P. M. Roekaerts, “Short-term outcomes and mortality after interhospital intensive care transportation: an observational prospective cohort study of 368 consecutive transports with a mobile intensive care unit,” BMJ Open, vol. 5, no. 4, pp. e006801–e006801, 2015. View at Publisher · View at Google Scholar
  100. A. Combes, D. Brodie, R. Bartlett et al., “Position paper for the organization of extracorporeal membrane oxygenation programs for acute respiratory failure in adult patients,” American Journal of Respiratory and Critical Care Medicine, vol. 190, no. 5, pp. 488–496, 2014. View at Publisher · View at Google Scholar · View at Scopus
  101. J. Javidfar, D. Brodie, A. Iribarne et al., “Extracorporeal membrane oxygenation as a bridge to lung transplantation and recovery,” Journal of Thoracic and Cardiovascular Surgery, vol. 144, no. 3, pp. 716–721, 2012. View at Publisher · View at Google Scholar · View at Scopus
  102. T. Fuehner, C. Kuehn, J. Hadem et al., “Extracorporeal membrane oxygenation in awake patients as bridge to lung transplantation,” American Journal of Respiratory and Critical Care Medicine, vol. 185, no. 7, pp. 763–768, 2012. View at Publisher · View at Google Scholar · View at Scopus
  103. C. W. Hoopes, J. Kukreja, J. Golden, D. L. Davenport, E. Diaz-Guzman, and J. B. Zwischenberger, “Extracorporeal membrane oxygenation as a bridge to pulmonary transplantation,” The Journal of Thoracic and Cardiovascular Surgery, vol. 145, no. 3, pp. 862–868, 2013. View at Publisher · View at Google Scholar
  104. M. Anile, D. Diso, E. Russo et al., “Extracorporeal membrane oxygenation as bridge to lung transplantation,” Transplantation Proceedings, vol. 45, no. 7, pp. 2621–2623, 2013. View at Publisher · View at Google Scholar · View at Scopus
  105. M. Nosotti, L. Rosso, D. Tosi et al., “Extracorporeal membrane oxygenation with spontaneous breathing as a bridge to lung transplantation,” Interactive Cardiovascular and Thoracic Surgery, vol. 16, no. 1, pp. 55–59, 2013. View at Publisher · View at Google Scholar · View at Scopus
  106. D. Chiumello, S. Coppola, S. Froio, A. Colombo, and L. Del Sorbo, “Extracorporeal life support as bridge to lung transplantation: a systematic review,” Critical Care, vol. 19, article 19, 2015. View at Publisher · View at Google Scholar · View at Scopus
  107. A. W. N. In‘t Veld-van Wingerden, J. Maas, H. I. J. Harinck, and R. Mauritz, “Long-term extracorporeal membrane oxygenation in acute respiratory distress syndrome,” Netherlands Journal of Critical Care, vol. 19, no. 1, pp. 20–24, 2015. View at Google Scholar · View at Scopus
  108. T. Strecker, F. Münch, and M. Weyand, “One hundred ten days of extracorporeal membrane oxygenation in a young woman with postpartum cerebral venous thrombosis and acute respiratory distress syndrome,” Heart Surgery Forum, vol. 15, no. 4, pp. E180–E181, 2012. View at Publisher · View at Google Scholar · View at Scopus
  109. D. C. Abrams, K. Prager, C. D. Blinderman, K. M. Burkart, and D. Brodie, “Ethical dilemmas encountered with the use of extracorporeal membrane oxygenation in adults,” Chest, vol. 145, no. 4, pp. 876–882, 2014. View at Publisher · View at Google Scholar · View at Scopus
  110. J. D. Hill, T. G. O'Brien, J. J. Murray et al., “Prolonged extracorporeal oxygenation for acute post-traumatic respiratory failure (shock-lung syndrome). Use of the Bramson membrane lung,” The New England Journal of Medicine, vol. 286, no. 12, pp. 629–634, 1972. View at Publisher · View at Google Scholar · View at Scopus
  111. H. de Paris and A. G. Maquet Cardiopulmonary, Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome, 2015.
  112. A. Haneya, A. Philipp, M. Foltan et al., “First experience with the new portable extracorporeal membrane oxygenation system Cardiohelp for severe respiratory failure in adults,” Perfusion, vol. 27, no. 2, pp. 150–155, 2012. View at Publisher · View at Google Scholar · View at Scopus
  113. R. Roncon-Albuquerque Jr., C. Basílio, P. Figueiredo et al., “Portable miniaturized extracorporeal membrane oxygenation systems for H1N1-related severe acute respiratory distress syndrome: a case series,” Journal of Critical Care, vol. 27, no. 5, pp. 454–463, 2012. View at Publisher · View at Google Scholar · View at Scopus
  114. A. S. Sharma, P. W. Weerwind, U. Strauch, A. van Belle, J. G. Maessen, and E. F. Wouters, “Applying a low-flow CO2 removal device in severe acute hypercapnic respiratory failure,” Perfusion, vol. 31, no. 2, pp. 149–155, 2016. View at Publisher · View at Google Scholar
  115. S. J. Han, H. S. Kim, K. Kim II et al., “Use of nafamostat mesilate as an anticoagulant during extracorporeal membrane oxygenation,” Journal of Korean Medical Science, vol. 26, no. 7, pp. 945–950, 2011. View at Publisher · View at Google Scholar · View at Scopus
  116. M. Larsson, V. Rayzman, M. W. Nolte et al., “Cardiovascular disease: a factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk,” Science Translational Medicine, vol. 6, no. 222, Article ID 222ra17, 2014. View at Publisher · View at Google Scholar · View at Scopus
  117. University Health Network: Toronto and The Physicians' Services Incorporated Foundation, Strategies for Optimal Lung Ventilation in ECMO for ARDS: The SOLVE ARDS Study, 2015.
  118. M. A. Noah, G. J. Peek, S. J. Finney et al., “Referral to an extracorporeal membrane oxygenation center and mortality among patients with severe 2009 influenza A(H1N1),” The Journal of the American Medical Association, vol. 306, no. 15, pp. 1659–1668, 2011. View at Publisher · View at Google Scholar · View at Scopus
  119. D. M. Guirand, O. T. Okoye, B. S. Schmidt et al., “Venovenous extracorporeal life support improves survival in adult trauma patients with acute hypoxemic respiratory failure: a multicenter retrospective cohort study,” Journal of Trauma and Acute Care Surgery, vol. 76, no. 5, pp. 1275–1281, 2014. View at Publisher · View at Google Scholar · View at Scopus