Role of BKCa in Stretch-Induced Relaxation of Colonic Smooth Muscle
Activation of B by membrane stretch in rat colonic SMCs. (a) The pressure-dependent activation of B channels was recorded from a cell-attached patch. The patches were held at +60 mV. (b) The expanded data show the amplitude of the single-channel current was not changed compared with that in other panels (C: closed state). (c) Statistical data of B channel open probability () challenged by negative pressure on cell-attached patch. Values are shown as means ± SEM, = 5; < 0.05 versus control group; < 0.05 versus −30 mmHg group.
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