Research Article

A New Transgenic Mouse Model of Heart Failure and Cardiac Cachexia Raised by Sustained Activation of Met Tyrosine Kinase in the Heart

Figure 6

Heat map of the gene expression profiling of wasting gastrocnemius muscle from cachectic Tpr-Met mice. Total RNA from gastrocnemius muscle (GSN) of cachectic Tpr-Met mice was compared to littermate controls. Standardization was applied to Log2 absolute intensities. A cut-off of and fold change >1.7 was used. Unsupervised hierarchical clustering was performed and the corresponding heat map was generated. 107 unique genes differentially expressed were identified.