Modic Changes and Disc Degeneration Caused by Inoculation of Propionibacterium acnes inside Intervertebral Discs of Rabbits: A Pilot Study

Table 1

Animal group information.

	Inoculated bacterial type	Numbers	Inoculated segment	Bacterial load	Dead or not
Group A	The wild-type strain of P. acnes isolated from patient	3	L6~L7	P. acnes suspension in sterilized TSB without bovine serum at 1 × 10^7 CFU/mL with 25 μL	All alive until the end of follow-up
			L5~L6	Sterilized TSB without bovine serum with 25 μL
Group B	The standard strain of P. acnes (ATCC 6919)	2	L6~L7	P. acnes suspension in sterilized TSB without bovine serum at 1 × 10^7 CFU/mL with 25 μL	All alive until the end of follow-up
			L5~L6	Sterilized TSB without bovine serum with 25 μL
Group C	The standard strain of S. aureus (ATCC 25923)	3	L6~L7	S. aureus suspension in sterilized saline at 1 × 10^7 CFU/mL with 25 μL	One died at the fourth week; One died at the fifth week; One alive until the end of follow-up
			L5~L6	Sterilized saline with 25 μL