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BioMed Research International
Volume 2016, Article ID 9781695, 8 pages
Review Article

Current Applications for the Use of Extracorporeal Carbon Dioxide Removal in Critically Ill Patients

Department of Adult Critical Care, Guy’s and St Thomas’ NHS Foundation Trust, King’s Health Partners, St Thomas’ Hospital, 1st Floor East Wing, Westminster Bridge Road, London SE1 7EH, UK

Received 1 December 2015; Accepted 20 January 2016

Academic Editor: Christophe Guervilly

Copyright © 2016 Luigi Camporota and Nicholas Barrett. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Mechanical ventilation in patients with respiratory failure has been associated with secondary lung injury, termed ventilator-induced lung injury. Extracorporeal venovenous carbon dioxide removal (ECCO2R) appears to be a feasible means to facilitate more protective mechanical ventilation or potentially avoid mechanical ventilation in select patient groups. With this expanding role of ECCO2R, we aim to describe the technology and the main indications of ECCO2R.