Review Article

Endothelial Microparticles Act as Novel Diagnostic and Therapeutic Biomarkers of Diabetes and Its Complications: A Literature Review

Table 4

The effects of drugs on plasma levels of EMPs in patients with DM.

Pharmacological effectsDrugsPatient or cellsThe effects of drugs on EMPsReferences

AntihypertensiveNifedipineT2DM with hypertensionDecrease[50]
LosartanT2DM with hypertensionDecrease[51]

AntiatherosclerosisSimvastatinHUVECIncrease[60]
Simvastatin + losartanT2DM with hyperlipidemia and hypertensionDecrease[51]
Eicosapentaenoic acidT2DM with hyperlipidemiaDecrease[52]
Vitamin CT2DM with acute myocardial infarctionDecrease[33]

AntihyperglycemicPioglitazoneT2DMDecrease[34]