Review Article

Hepatitis E Virus in Industrialized Countries: The Silent Threat

Table 1

Seroprevalence values reported among general population and blood donors in different European countries.

CountryGroupNumber of  samples (year)AssaySeroprevalenceReference

UKGP1591 (2004)FD13% [25]
1140 (1991)13.5%
Southwest EnglandBD487W15.8%[26]
ScotlandBD1559W4.7%[27]
IrelandBD1076W5.3%[28]
NorwayBD1200W14%[29]
FranceBD10569W22.4%[30]
Southwestern FranceBD512W52.2%[31]
DenmarkBD504W19.8% [32]
NIH10.7%
NetherlandsBD5239W26.7%[33]
SpainGP1280BK7.3%[34]
SpainGP2305HA2.17%[35]
SpainBD1082W19.97% [36]
MK10.72%
GermanyGP1092 (2011)Ax34.3% [37]
1092 (1996)50.7%
GermanyGP4422rL16.8%[38]
Southwest SwitzerlandBD550MP4.9% [39]
DP4.2%
FD21.8%
GreeceBD265Adaltis9.43%[40]

GP = general population.
BD = blood donors.
Assays: FD = Fortress Diagnostics (identical to Wantai), W = Wantai, NIH = NIH in-house assay, BK = Biokit, HA = HEV Ab, MK = Mikrogen ELISA test, Ax = Axcom, MP = MP Diagnostics, DP/A = Dia.Pro/Adaltis, and rL = recomLine Mikrogen (Western Blot).