Diagnostics of Thyroid Malignancy and Indications for Surgery in the Elderly and Younger Counterparts: Comparison of 3,749 Patients
Table 1
Baseline characteristics of 3,749 patients with thyroid nodules.
Parameters
Mean ± SD or (%)
Age (years)
51.4 ± 14.4
Gender
Female
3,148 (84.0)
Male
601 (16.0)
Cytological diagnosis according to TBSRTC
Stage II (normotype thyrocytes, lymphocytes, thyroiditis suspicion)
3,206 (85.5)
Stage III (AUS/FLUS)
84 (2.2)
Stage IV (follicular neoplasm)
225 (6.0)
Stage V (malignancy suspicion)
48 (1.3)
Stage V (malignancy/lymphoma suspicion)
2 (0.1)
Stage VI (papillary carcinoma)
178 (4.7)
Stage VI (medullary carcinoma)
6 (0.2)
Clinical suspicion of malignancy
No
3,290 (87.8)
Yes
459 (12.2)
Histological diagnosis
Benign multinodular goiter
2,946 (78.6)
Thyroiditis
118 (3.1)
Follicular carcinoma
25 (0.7)
Papillary carcinoma
247 (6.6)
Medullary carcinoma
10 (0.3)
Undifferentiated thyroid carcinoma
9 (0.3)
Secondary malignant tumor
4 (0.1)
Lymphoma
9 (0.2)
Follicular adenoma
375 (10.0)
Squamous cell carcinoma
1 (0.03)
Abscess
1 (0.03)
Final diagnosis
Benign
3,440 (91.8)
Malignant
309 (8.2)
TBSRTC: The Bethesda System for Reporting Thyroid Cytology, Second Edition 2010 Bethesda, Maryland; AUS: atypia of undetermined significance; FLUS: follicular lesion of undetermined significance.
