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Research Article
BioMed Research International
Volume 2017, Article ID 1357109, 2 pages
https://doi.org/10.1155/2017/1357109
Corrigendum

Corrigendum to “Dual Inhibiting Senescence and Epithelial-to-Mesenchymal Transition by Erythropoietin Preserve Tubular Epithelial Cell Regeneration and Ameliorate Renal Fibrosis in Unilateral Ureteral Obstruction”

1Nephrology Unit, Department of Medicine, Faculty of Medicine, Thammasat University (Rangsit Campus), Khlong Nueng, Khlong Luang, Pathum Thani 12121, Thailand
2Division of Biochemistry, Department of Preclinical Sciences, Faculty of Medicine, Thammasat University (Rangsit Campus), Khlong Nueng, Khlong Luang, Pathum Thani 12121, Thailand
3Department of Paediatric, Faculty of Medicine, Thammasat University (Rangsit Campus), Khlong Nueng, Khlong Luang, Pathum Thani 12121, Thailand

Correspondence should be addressed to Supranee Kongkham; moc.oohay@mahkgnokus

Received 3 November 2016; Accepted 9 November 2016; Published 19 March 2017

Copyright © 2017 Adis Tasanarong et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In the article titled “Dual Inhibiting Senescence and Epithelial-to-Mesenchymal Transition by Erythropoietin Preserve Tubular Epithelial Cell Regeneration and Ameliorate Renal Fibrosis in Unilateral Ureteral Obstruction” [1], there was an error in Figure , where the picture for EPO/Sham in the Smad2/3 was incorrect.

The correct EPO/Sham picture is shown in Figure 3.

Figure 3: Representative photographs of kidney sections stained with TGF-β, BMP-7, Smad2/3, and in UUO model. In sham kidneys, no or little TGF-β labelling was seen. Advance increased TGF-β labelling was seen in the interstitium area in the obstructed kidneys compared with the sham at days 3, 7, and 14. In contrast, decreased of TGF-β staining was observed in UUO mice with rhEPO treatment. In contrast, BMP-7 was demonstrated in the cytoplasm of TEC in sham kidneys, whereas the labeling of BMP-7 was decreased in cytoplasm of TEC particularly in dilated and atrophic tubules of the placebo treated UUO kidneys since day 3 after UUO and progressively loss until day 14. rhEPO treatment in mice with UUO demonstrated the significantly preserved the cytoplasm staining intensity of BMP-7 in the obstructed kidneys. Moreover, no Smad2/3 and staining was seen in TEC in sham kidneys. Smad2/3 and are detected at the nucleus of TEC with weak cytoplasm staining particularly in dilated and atrophic tubules of the UUO kidneys since days 3, 7, and 14. In contrast, rhEPO treatment in mice with UUO demonstrated the significantly attenuated nucleus and cytoplasm staining intensity of Smad2/3 and in the obstructed kidneys. Original magnifications ×400.

References

  1. A. Tasanarong, S. Kongkham, and S. Khositseth, “Dual inhibiting senescence and epithelial-to-mesenchymal transition by erythropoietin preserve tubular epithelial cell regeneration and ameliorate renal fibrosis in unilateral ureteral obstruction,” BioMed Research International, vol. 2013, Article ID 308130, 12 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus