Serum Butyrylcholinesterase Activity: A Biomarker for Parkinson’s Disease and Related Dementia

Table 2

Univariate and multivariate linear regression analysis of correlation factors for serum butyrylcholinesterase activity.

Variable	Univariate		Multivariate
	Beta value	value	Beta value	value
Age	−0.264	0.002	—	—
Gender	0.258	0.002	0.183	0.006
Albumin	0.477	0.000	0.350	0.000
ALT	−0.014	0.867	/	/
AST	−2.052	0.042	—	—
TC	3.876	0.000	—	—
TG	0.439	0.000	0.235	0.001
BMI	0.322	0.000	0.163	0.020
Smoking history	−0.028	0.744	/	/
Alcohol consumption	−0.001	0.991	/	/
Hypertension	0.074	0.392	/	/
Diabetes mellitus	0.059	0.496	/	/
Hypercholesterolaemia	0.166	0.052	—	—
CHD	−0.090	0.297	/	/
PD	−0.347	0.000	−0.240	0.000

Beta value, adjusted regression coefficient; ALT, alanine transaminase; AST, aspartate aminotransferase; TC, total cholesterol; TG, triglyceride; BMI, body mass index; CHD, coronary heart disease; PD, Parkinson’s disease.
For the multivariate linear regression analysis using a backward method based on the results from univariate linear regression analysis, the values were “/” if variables were excluded before the analysis, and the values were “—” if variables were excluded after the analysis.