Association of Platelet Membrane Glycoprotein HPA-2a/b, GP VI T13254C, and GP Ibα VNTR Polymorphisms with Risk of Coronary Artery Disease: A Meta-Analysis

Table 2

Meta-analysis of studies examining association between HPA-2a/b polymorphisms and risk of coronary artery disease according to race.

Genotype	Number of trails	Heterogeneity		Effect model	Meta-analyses
			value		ORs	95% CIs	value
Allelic model
All	15	78	<0.01	Random	1.43	1.07–1.91	0.01
Race
Caucasian	7	48	0.07	Fixed	1.40	1.06–1.84	0.02
East Asians	6	84	<0.01	Random	1.95	1.09–3.50	0.03
Indian	2	0%	0.48	Fixed	0.75	0.55–1.04	0.08
Dominant model
All	15	84	<0.01	Random	1.57	1.08–2.28	0.02
Race
Caucasian	6	63	0.02	Random	1.46	1.00–2.14	0.05
East Asians	7	89	<0.01	Random	2.23	1.06–4.71	0.04
Indian	2	0%	0.45	Fixed	0.75	0.54–1.05	0.10