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BioMed Research International
Volume 2017, Article ID 1681392, 7 pages
https://doi.org/10.1155/2017/1681392
Research Article

The Influence of Different Oregano Species on the Antioxidant Activity Determined Using HPLC Postcolumn DPPH Method and Anticancer Activity of Carvacrol and Rosmarinic Acid

1Department of Drugs Technology and Social Pharmacy, Lithuanian University of Health Sciences, Medical Academy, Kaunas, Lithuania
2Department of Analytical and Toxicological Chemistry, Lithuanian University of Health Sciences, Medical Academy, Kaunas, Lithuania
3Department of Drug Chemistry, Lithuanian University of Health Sciences, Medical Academy, Kaunas, Lithuania

Correspondence should be addressed to Juste Baranauskaite; moc.liamg@etsuj.etiaksuanarab

Received 21 February 2017; Revised 12 April 2017; Accepted 27 August 2017; Published 18 October 2017

Academic Editor: Gail B. Mahady

Copyright © 2017 Juste Baranauskaite et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. V. K. Gupta and S. K. Sharma, “Plants as natural antioxidants,” Natural Product Radiance, vol. 5, no. 4, pp. 326–334, 2006. View at Google Scholar
  2. N. Nakatani, “Antioxidants from spices and herbs,” in Natural Antioxidants: Chemistry, Health Effects and Applications, pp. 64–75, AOAC Press, Champaign, Ill, USA, 1997. View at Publisher · View at Google Scholar
  3. N. V. Yanishlieva, E. Marinova, and J. Pokorný, “Natural antioxidants from herbs and spices,” European Journal of Lipid Science and Technology, vol. 108, no. 9, pp. 776–793, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. T. Kulisic, A. Radonic, V. Katalinic, and M. Milos, “Use of different methods for testing antioxidative activity of oregano essential oil,” Food Chemistry, vol. 85, no. 4, pp. 633–640, 2004. View at Publisher · View at Google Scholar · View at Scopus
  5. G. Ozkan, H. Baydar, and S. Erbas, “The influence of harvest time on essential oil composition, phenolic constituents and antioxidant properties of Turkish oregano (Origanum onites L.),” Journal of the Science of Food and Agriculture, vol. 90, no. 2, pp. 205–209, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. T. Kulišić, V. Dragović-Uzelac, and M. Miloš, “Antioxidant activity of aqueous tea infusions prepared from oregano, thyme and wild thyme,” Food Technology and Biotechnology, vol. 44, no. 4, pp. 485–492, 2006. View at Google Scholar · View at Scopus
  7. P. R. Quiroga, N. R. Grosso, A. Lante, G. Lomolino, J. A. Zygadlo, and V. Nepote, “Chemical composition, antioxidant activity and anti-lipase activity of Origanum vulgare and Lippia turbinata essential oils,” International Journal of Food Science and Technology, vol. 48, no. 3, pp. 642–649, 2013. View at Publisher · View at Google Scholar · View at Scopus
  8. E. De Falco, E. Mancini, G. Roscigno, E. Mignola, O. Taglialatela-Scafati, and F. Senatore, “Chemical composition and biological activity of essential oils of origanum vulgare L. subsp. vulgare L. under different growth conditions,” Molecules, vol. 18, no. 12, pp. 14948–14960, 2013. View at Publisher · View at Google Scholar · View at Scopus
  9. K. H. C. Baser, “Biological and pharmacological activities of carvacrol and carvacrol bearing essential oils,” Current Pharmaceutical Design, vol. 14, no. 29, pp. 3106–3119, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. M. Koşar, D. Dorman, K. Başer, and R. Hiltunen, “An improved HPLC post-column methodology for the identification of free radical scavenging phytochemicals in complex mixtures,” Chromatographia, vol. 60, no. 11-12, pp. 635–638, 2004. View at Publisher · View at Google Scholar · View at Scopus
  11. A. Özkan and A. Erdoǧan, “A comparative evaluation of antioxidant and anticancer activity of essential oil from origanum onites (lamiaceae) and its two major phenolic components,” Turkish Journal of Biology, vol. 35, no. 6, pp. 735–742, 2011. View at Publisher · View at Google Scholar · View at Scopus
  12. N. V. Yanishlieva, E. M. Marinova, M. H. Gordon, and V. G. Raneva, “Antioxidant activity and mechanism of action of thymol and carvacrol in two lipid systems,” Food Chemistry, vol. 64, no. 1, pp. 59–66, 1999. View at Publisher · View at Google Scholar · View at Scopus
  13. G. Ruberto and M. T. Baratta, “Antioxidant activity of selected essential oil components in two lipid model systems,” Food Chemistry, vol. 69, no. 2, pp. 167–174, 2000. View at Publisher · View at Google Scholar · View at Scopus
  14. H. Ibrahim, E. Caudron, A. Kasselouri, and P. Prognon, “Interest of fluorescence derivatization and fluorescence probe assisted post-column detection of phospholipids: a short review,” Molecules, vol. 15, no. 1, pp. 352–373, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. R. Raudonis, L. Raudone, V. Jakstas, and V. Janulis, “Comparative evaluation of post-column free radical scavenging and ferric reducing antioxidant power assays for screening of antioxidants in strawberries,” Journal of Chromatography A, vol. 1233, no. 13, pp. 8–15, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Camenzuli, H. J. Ritchie, G. R. Dennis, and R. A. Shalliker, “Reaction flow chromatography for rapid post column derivatisations: The analysis of antioxidants in natural products,” Journal of Chromatography A, vol. 1303, pp. 62–65, 2013. View at Publisher · View at Google Scholar · View at Scopus
  17. M. Marksa, J. Radušiene, V. Jakštas, L. Ivanauskas, and R. Marksiene, “Development of an HPLC post-column antioxidant assay for Solidago canadensis radical scavengers,” Natural Product Research, vol. 30, no. 5, pp. 536–543, 2016. View at Publisher · View at Google Scholar · View at Scopus
  18. J. Baranauskaite, V. Jakštas, L. Ivanauskas et al., “Optimization of carvacrol, rosmarinic, oleanolic and ursolic acid extraction from oregano herbs (Origanum onites L., Origanum vulgare spp. hirtum and Origanum vulgare L.),” Natural Product Research, vol. 30, no. 6, pp. 672–674, 2016. View at Publisher · View at Google Scholar · View at Scopus
  19. Y. P. Zhang, S. Y. Shi, X. Xiong, X. Q. Chen, and M. J. Peng, “Comparative evaluation of three methods based on high-performance liquid chromatography analysis combined with a 2,2-diphenyl-1-picrylhydrazyl assay for the rapid screening of antioxidants from Pueraria lobata flowers,” Analytical and Bioanalytical Chemistry, vol. 402, no. 9, pp. 2965–2976, 2012. View at Publisher · View at Google Scholar · View at Scopus
  20. S.-Y. Shi, Y.-P. Zhang, X.-Y. Jiang, X.-Q. Chen, K.-L. Huang, and H.-H. Zhou, “Coupling HPLC to on-line, post-column (bio)chemical assays for high-resolution screening of bioactive compounds from complex mixtures,” Trends in Analytical Chemistry, vol. 28, no. 7, pp. 865–877, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. R. Yan, Y. Cao, and B. Yang, “HPLC-DPPH screening method for evaluation of antioxidant compounds extracted from semen oroxyli,” Molecules, vol. 19, no. 4, pp. 4409–4417, 2014. View at Publisher · View at Google Scholar · View at Scopus
  22. H. J. D. Dorman, O. Bachmayer, M. Kosar, and R. Hiltunen, “Antioxidant properties of aqueous extracts from selected Lamiaceae species grown in Turkey,” Journal of Agricultural and Food Chemistry, vol. 52, no. 4, pp. 762–770, 2004. View at Publisher · View at Google Scholar · View at Scopus
  23. H. L. Madsen, B. R. Nielsen, G. Bertelsen, and L. H. Skibsted, “Screening of antioxidative activity of spices. A comparison between assays based on ESR spin trapping and electrochemical measurement of oxygen consumption,” Food Chemistry, vol. 57, no. 2, pp. 331–337, 1996. View at Publisher · View at Google Scholar · View at Scopus
  24. L. Pizzale, R. Bortolomeazzi, S. Vichi, E. Überegger, and L. S. Conte, “Antioxidant activity of sage (Salvia officinalis and S fruticosa) and oregano (Origanum onites and O indercedens) extracts related to their phenolic compound content,” Journal of the Science of Food and Agriculture, vol. 82, no. 14, pp. 1645–1651, 2002. View at Publisher · View at Google Scholar · View at Scopus
  25. A. Tomaino, F. Cimino, V. Zimbalatti et al., “Influence of heating on antioxidant activity and the chemical composition of some spice essential oils,” Food Chemistry, vol. 89, no. 4, pp. 549–554, 2005. View at Publisher · View at Google Scholar · View at Scopus
  26. M. Viuda-Martos, Y. R. Navajas, E. S. Zapata, J. Fernández-López, and J. A. Pérez-Álvarez, “Antioxidant activity of essential oils of five spice plants widely used in a Mediterranean diet,” Flavour and Fragrance Journal, vol. 25, no. 1, pp. 13–19, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. D.-O. Moon, M.-O. Kim, J.-D. Lee, Y. H. Choi, and G.-Y. Kim, “Rosmarinic acid sensitizes cell death through suppression of TNF-α-induced NF-κB activation and ROS generation in human leukemia U937 cells,” Cancer Letters, vol. 288, no. 2, pp. 183–191, 2010. View at Publisher · View at Google Scholar · View at Scopus
  28. O. Yesil-Celiktas, C. Sevimli, E. Bedir, and F. Vardar-Sukan, “Inhibitory effects of rosemary extracts, carnosic acid and rosmarinic acid on the growth of various human cancer cell lines,” Plant Foods for Human Nutrition, vol. 65, no. 2, pp. 158–163, 2010. View at Publisher · View at Google Scholar · View at Scopus
  29. K. M. Arunasree, “Anti-proliferative effects of carvacrol on a human metastatic breast cancer cell line, MDA-MB 231,” Phytomedicine, vol. 17, no. 8, pp. 581–588, 2010. View at Google Scholar
  30. S. J. Mehdi, A. Ahmad, M. Irshad, N. Manzoor, and M. M. A. Rizvi, “Cytotoxic effect of carvacrol on human cervical cancer cells,” Biology and Medicine, vol. 3, no. 2, pp. 307–312, 2011. View at Google Scholar
  31. R. Mangum and I. Nakano, “Glioma stem cells and their therapy resistance,” Journal of Carcinogenesis and Mutagenesis, vol. 1, 2011. View at Google Scholar
  32. J. Moore, M. Yousef, and E. Tsiani, “Anticancer effects of rosemary (Rosmarinus officinalis L.) extract and rosemary extract polyphenols,” Nutrients, vol. 8, no. 11, p. 731, 2016. View at Google Scholar