Healing and Antisecretory Effects of Aqueous Extract of Eremomastax speciosa (Acanthaceae) on Unhealed Gastric Ulcers

Table 8

Antioxidant effects of E. speciosa in rats subjected to “unhealed gastric ulcers”/pylorus ligature/histamine.

Treatment	Dose (mg/kg)	SOD; (U/mg protein)	Catalase; (µmol H2O2/min/mg protein)	GSH; (mmol/g protein)	Malondialdehyde; (pmol/mg protein)
Normal rats	—	7.54 ± 0.16	5.22 ± 0.22	2.61 ± 0.02	1.60 ± 0.07
Control 1	—	4.02 ± 1.53	0.54 ± 0.03	0.85 ± 0.80	4.04 ± 0.25
Control 2	—	4.57 ± 0.38	0.71 ± 0.04	0.85 ± 0.20	4.24 ± 0.29
E. speciosa	200	5.75 ± 0.33	4.14 ± 0.25	2.69 ± 0.17	2.35 ± 0.37
E. speciosa	400	7.42 ± 0.19	5.94 ± 0.45	3.62 ± 0.48	1.46 ± 0.11

= 5 rats per treatment. Control 1: ulcerated rats sacrificed 5 days after ulcer induction. The values are expressed as mean ± SEM; < 0.05; < 0.01; < 0.001; statistically different compared to normal rats; < 0.01; < 0.001; statistically different compared to Control 2; Control 1 or 4th day control; Control 2 or vehicle control. and compared with Control 1.