MicroRNA-195 Activates Hepatic Stellate Cells In Vitro by Targeting Smad7
TGF-β1 promotes HSC-T6 proliferation and miR-195 transcription. (a) MTT assays for cell proliferation with different concentrations of TGF- (1 ng/mL, 2 ng/mL, 4 ng/mL, 6 ng/mL, and 8 ng/mL) at 24 h, 48 h, and 72 h. versus control (24 h); , versus control (48 h); , versus control (72 h). (b) miR-195 expression in HSC-T6 cells treated with TGF- (2 ng/mL, 5 ng/mL, and 10 ng/mL) for 24 h. versus control. versus TGF- (2 ng/mL). Each value represents the mean ± SD of three experiments.
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.