Mesenchymal Stem Cells Attenuate Radiation-Induced Brain Injury by Inhibiting Microglia Pyroptosis

Figure 1

Radiation increased cortex NLRP3 inflammasome and caspase-1 expression in vivo. (a) Immunofluorescence assay proved that increased NLRP3 inflammasome expression was induced by radiation in vivo. (b) Western blotting analysis demonstrated that mice brains exposed to 15 Gy radiation had increased expression of NLRP3 inflammasome and caspase-1. Bars represent mean ± SEM. 7. Scale bar indicates 50 m. and versus the control group (con); ns means no significance.

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