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BioMed Research International
Volume 2017, Article ID 2017493, 12 pages
https://doi.org/10.1155/2017/2017493
Research Article

Electrospun Nanofibers Loaded with Quercetin Promote the Recovery of Focal Entrapment Neuropathy in a Rat Model of Streptozotocin-Induced Diabetes

1Department of Physiology and Graduate School (Neuroscience Program), Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
2Integrative Complementary and Alternative Medicine Research and Development Center, Khon Kaen University, Khon Kaen 40002, Thailand
3Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand

Correspondence should be addressed to Jintanaporn Wattanathorn; moc.oohay@wnropanatnij

Received 17 October 2016; Accepted 29 December 2016; Published 30 January 2017

Academic Editor: Stelvio M. Bandiera

Copyright © 2017 Chonlathip Thipkaew et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. L. Dellon, “A cause for optimism in diabetic neuropathy,” Annals of Plastic Surgery, vol. 20, no. 2, pp. 103–105, 1988. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Jakobsen, “Peripheral nerves in early experimental diabetes: expansion of the endoneurial space as a cause of increased water content,” Diabetologia, vol. 14, no. 2, pp. 113–119, 1978. View at Publisher · View at Google Scholar · View at Scopus
  3. K. H. Gabbay, N. Spack, S. Loo, H. J. Hirsch, and A. A. Ackil, “Aldose reductase inhibition: studies with alrestatin,” Metabolism, vol. 28, no. 4, pp. 471–476, 1979. View at Publisher · View at Google Scholar · View at Scopus
  4. B. E. Layton, A. M. Sastry, H. Wang et al., “Differences between collagen morphologies, properties and distribution in diabetic and normal biobreeding and Sprague-Dawley rat sciatic nerves,” Journal of Biomechanics, vol. 37, no. 6, pp. 879–888, 2004. View at Publisher · View at Google Scholar · View at Scopus
  5. R.-J. Chen, C.-C. K. Lin, and M.-S. Ju, “In situ biomechanical properties of normal and diabetic nerves: an efficient quasi-linear viscoelastic approach,” Journal of Biomechanics, vol. 43, no. 6, pp. 1118–1124, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. C. Lanza, S. Raimondo, L. Vergani et al., “Expression of antioxidant molecules after peripheral nerve injury and regeneration,” Journal of Neuroscience Research, vol. 90, no. 4, pp. 842–848, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. D. A. Greene, M. J. Stevens, I. Obrosova, and E. L. Feldman, “Glucose-induced oxidative stress and programmed cell death in diabetic neuropathy,” European Journal of Pharmacology, vol. 375, no. 1-3, pp. 217–223, 1999. View at Publisher · View at Google Scholar · View at Scopus
  8. N. E. Cameron, M. A. Cotter, V. Archibald, K. C. Dines, and E. K. Maxfield, “Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats,” Diabetologia, vol. 37, no. 5, pp. 449–459, 1994. View at Publisher · View at Google Scholar · View at Scopus
  9. A. A. Gerritsen, H. C. de Vet, R. J. Scholten, F. W. Bertelsmann, M. C. de Krom, and L. M. Bouter, “Splinting vs surgery in the treatment of carpal tunnel syndrome: a randomized controlled trial,” Japan Automobile Manufacturers Association, vol. 288, pp. 1245–1251, 2002. View at Google Scholar
  10. M. Zhang, S. G. Swarts, L. Yin et al., “Antioxidant properties of quercetin,” Advances in experimental medicine and biology, vol. 701, pp. 283–289, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. L. Biasutto, A. Mattarei, N. Sassi et al., “Improving the efficacy of plant polyphenols,” Anti-Cancer Agents in Medicinal Chemistry, vol. 14, no. 10, pp. 1332–1342, 2014. View at Publisher · View at Google Scholar · View at Scopus
  12. M. Comalada, D. Camuesco, S. Sierra et al., “In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-κB pathway,” European Journal of Immunology, vol. 35, no. 2, pp. 584–592, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. R. Kleemann, L. Verschuren, M. Morrison et al., “Anti-inflammatory, anti-proliferative and anti-atherosclerotic effects of quercetin in human in vitro and in vivo models,” Atherosclerosis, vol. 218, no. 1, pp. 44–52, 2011. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Vessal, M. Hemmati, and M. Vasei, “Antidiabetic effects of quercetin in streptozocin-induced diabetic rats,” Comparative Biochemistry and Physiology—C Toxicology and Pharmacology, vol. 135, no. 3, pp. 357–364, 2003. View at Publisher · View at Google Scholar · View at Scopus
  15. F. Perez-Vizcaino, J. Duarte, R. Jimenez, C. Santos-Buelga, and A. Osuna, “Antihypertensive effects of the flavonoid quercetin,” Pharmacological Reports, vol. 61, no. 1, pp. 67–75, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. N. Haleagrahara, C. J. Siew, N. K. Mitra, and M. Kumari, “Neuroprotective effect of bioflavonoid quercetin in 6-hydroxydopamine-induced oxidative stress biomarkers in the rat striatum,” Neuroscience Letters, vol. 500, no. 2, pp. 139–143, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. A. D. Kandhare, K. S. Raygude, V. Shiva Kumar et al., “Ameliorative effects quercetin against impaired motor nerve function, inflammatory mediators and apoptosis in neonatal streptozotocin-induced diabetic neuropathy in rats,” Biomedicine & Aging Pathology, vol. 2, no. 4, pp. 173–186, 2012. View at Publisher · View at Google Scholar · View at Scopus
  18. P. Pangphukiew, J. Wattanathorn, S. Muchimapura, and W. Thkham-mee, “Quercetin-loaded zein based nanofiber patch: a novel cognitive enhancer,” International Journal of Pharmacy and Biomedical Sciences, vol. 3, no. 3, pp. 103–108, 2012. View at Google Scholar
  19. O. H. Lowry, N. J. Rosebrough, A. L. Farr, and R. J. Randall, “Protein measurement with the folin phenol reagent,” The Journal of Biological Chemistry, vol. 193, no. 1, pp. 265–275, 1951. View at Google Scholar · View at Scopus
  20. H. Ohkawa, N. Ohishi, and K. Yagi, “Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction,” Analytical Biochemistry, vol. 95, no. 2, pp. 351–358, 1979. View at Publisher · View at Google Scholar · View at Scopus
  21. P. Taepaiboon, U. Rungsardthong, and P. Supaphol, “Vitamin-loaded electrospun cellulose acetate nanofiber mats as transdermal and dermal therapeutic agents of vitamin A acid and vitamin E,” European Journal of Pharmaceutics and Biopharmaceutics, vol. 67, no. 2, pp. 387–397, 2007. View at Publisher · View at Google Scholar · View at Scopus
  22. X.-Y. Li, C.-J. Shi, D.-G. Yu, Y.-Z. Liao, and X. Wang, “Electrospun quercetin-loaded zein nanoribbons,” Bio-Medical Materials and Engineering, vol. 24, no. 6, pp. 2015–2023, 2014. View at Publisher · View at Google Scholar · View at Scopus
  23. T. M. Reeves, L. L. Phillips, and J. T. Povlishock, “Myelinated and unmyelinated axons of the corpus callosum differ in vulnerability and functional recovery following traumatic brain injury,” Experimental Neurology, vol. 196, no. 1, pp. 126–137, 2005. View at Publisher · View at Google Scholar · View at Scopus
  24. J. Hofmeijer, H. Franssen, L. J. van Schelven, and M. J. A. M. van Putten, “Why are sensory axons more vulnerable for ischemia than motor axons?” PLoS ONE, vol. 8, no. 6, Article ID e67113, 2013. View at Publisher · View at Google Scholar · View at Scopus
  25. S. Rotshenker, “Wallerian degeneration: the innate-immune response to traumatic nerve injury,” Journal of Neuroinflammation, vol. 8, article no. 109, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. M. Senoglu, V. Nacitarhan, E. B. Kurutas et al., “Intraperitoneal Alpha-Lipoic Acid to prevent neural damage after crush injury to the rat sciatic nerve,” Journal of Brachial Plexus and Peripheral Nerve Injury, vol. 4, no. 1, article 22, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. S. L. Fyffe-Maricich, A. Schott, M. Karl, J. Krasno, and R. H. Miller, “Signaling through ERK1/2 controls myelin thickness during myelin repair in the adult central nervous system,” The Journal of Neuroscience, vol. 33, no. 47, pp. 18402–18408, 2013. View at Publisher · View at Google Scholar · View at Scopus
  28. J. Y. Sheu, D. J. Kulhanek, and F. P. Eckenstein, “Differential patterns of ERK and STAT3 phosphorylation after sciatic nerve transection in the rat,” Experimental Neurology, vol. 166, no. 2, pp. 392–402, 2000. View at Publisher · View at Google Scholar · View at Scopus