α-MSH Influences the Excitability of Feeding-Related Neurons in the Hypothalamus and Dorsal Vagal Complex of Rats

Figure 8

Effect of α-MSH on GD-EXC neurons in the DVC. (a) Typical frequency histograms show that GD-EXC neurons were activated by α-MSH. The first arrow indicates gastric distention, the second arrow indicates α-MSH (500 nM), and the third arrow indicates a 0.9% NaCl treated control. (b) Typical frequency histograms show that SHU9119 partially abolished the effects of α-MSH on GD-EXC neurons in the DVC. The first arrow indicates gastric distention, the second arrow indicates α-MSH (500 nM), the third arrow indicates pretreatment with SHU9119 (1 μM), and the fourth arrow indicates another injection of α-MSH.

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