Magnetic Resonance Elastography Shear Wave Velocity Correlates with Liver Fibrosis and Hepatic Venous Pressure Gradient in Adults with Advanced Liver Disease

Table 1

Baseline demographic and clinical characteristics of study subjects ().

Parameter
Age, years	54 (45–76)
Male, (%)	18 (78%)
Liver disease etiology, (%)
HCV	9 (39%)
HCV/HIV	9 (39%)
HIV/NASH	5 (22%)
Body mass index, kg/m^2	30 (21–46)
>30 kg/m^2 (obesity), (%)	12 (52%)
Laboratory studies
Platelets, K/uL	159 (45–284)
Alkaline phosphatase, U/L	107 (51–210)
Aspartate aminotransferase (AST), U/L	56 (22–151)
Alanine aminotransferase (ALT), U/L	77 (30–161)
Total bilirubin, mg/dL	0.8 (0.3–2.3)
Direct bilirubin, mg/dL	0.3 (0.1–1.4)
Gamma-glutamyl transferase (GGT), U/L	150 (19–531)
Albumin, g/dL	4.1 (3.0–5.5)
Prothrombin time (PT), seconds	14.3 (12.3–16.4)
International normalized ratio (INR)	1.1 (0.9–1.3)
Hepatitis C characteristics ()
HCV viral load, , IU/mL	6.9 (4.7–7.8)
Hepatitis C genotype, (%)
1a	13 (72)
1b	3 (17)
2	1 (6)
4	1 (6)
MRE shear wave velocity, m/sec ()	2.13 (1.25–3.03)
HVPG, mmHg	6 (3–16)
Liver biopsy length, mm	12 (6–24)
<10 mm, (%)	6 (26)
Liver biopsy scoring
Fibrosis, Ishak (range 0–6)	4 (1–6)
Inflammation, total HAI (range 0–18)	8 (1–14)
Steatosis (range 0–4)	1 (0–2)

Median, range presented unless otherwise noted.