Review Article

Cucurbitaceae Seed Protein Hydrolysates as a Potential Source of Bioactive Peptides with Functional Properties

Table 2

Polypeptides and oligopeptides with different bioactive properties in vitro identified in Cucurbitaceae seed proteins.

SourceSequenceMolecular weight (kDa)PropertiesReference

Pumpkin (Cucurbita maxima)KRDPDWRREQEERREQERRREQQQQRREEQQRGER12.33Antifungal Vassiliou et al. [35]
YTRGGRGGWKGGGGGKGGGGGKGGGGG2.34

Pumpkin (Cucurbita moschata cv. black pumpkin)PQRGEGGRAGNLLREEQEI~9AntifungalWang and Ng [36]

Momordica cochinchinensisGCEGKQCGLFRSCGGGCRCWPTVTPGVGICSSS3.29Anticarcinogenic Chan et al. [37]
GCEGKPCGLFRSCGGGCRCWPTVTPGVGICSS3.17

Benincasa hispidaSDYLNNNPLFPRYDIGNVELSTAYRSFANQKAPGRLNQNWALTADYTYR5.75Antimicrobial and antioxidantSharma et al. [38]

Bitter melon (Momordica charantia)FREKVYNIPL1.28ACE-inhibitory activity Priyanto et al. [33]
VSGAGRY0.71
ITLPYSGNYER1.31
IAAGKPREKIP1.18
IAAGKPREKIPIGLPA1.63
LLHYDSTAAAGALLVLIQTTAEAAR2.57
LHYDSTAAAGALLVLIQTTAEAAR2.46
LAQGNNGIFRTPIVL1.61
IFRTPIVL0.96
VDNKGNR0.80
FFKESPPEA1.05
FFKESPPEAYN1.33
IISLENQWSA1.16
FRNPVDL0.86
QASESLN0.75
LRYDDGWM1.05
IVLSSATDKGNGQQWT1.70