Gender Differences in the Progression of Experimental Chronic Kidney Disease Induced by Chronic Nitric Oxide Inhibition

Table 1

Functional and renal parameters observed after 30 days of treatment.

	Control ♂	Control ♀	NAME ♂	NAME ♀
BW (g)	336 ± 7
ΔBWG	31 ± 9	27 ± 1	4 ± 7
BP (mmHg)	127 ± 1	131 ± 5
24 h UAE (mg/24 h)	1.4 ± 0.5	1.4 ± 0.5

Values are presented as mean ± SEM for body weight (BW, g), body weight gain (ΔBWG), blood pressure measured by tail cuff pressure (Blood Pressure, mmHg), and 24 h urinary albumin excretion rate (24 h-UAE, mg/24 h). The number of animals studied per group was, respectively, Control ♂: ; Control ♀: ; NAME ♂: ; NAME ♂: . One-way analysis of variance with pairwise comparisons according to the Newman-Keuls method was used to compare experimental groups: versus Control ♂; versus Control ♀; versus NAME ♂.