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BioMed Research International
Volume 2017, Article ID 2351037, 5 pages
https://doi.org/10.1155/2017/2351037
Research Article

Acinetobacter baumannii Infection in Transfusion Dependent Thalassemia Patients with Sepsis

Department of Clinical Laboratory Science, College of Applied Medical Sciences, University of Dammam, Dammam, Saudi Arabia

Correspondence should be addressed to Muzaheed Abdul Rasheed; as.ude.dou@deehsaram

Received 9 February 2017; Revised 27 April 2017; Accepted 30 April 2017; Published 17 May 2017

Academic Editor: Paola Di Carlo

Copyright © 2017 Muzaheed Abdul Rasheed et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose. To identify the Acinetobacter baumannii infection among transfusion dependent thalassemia patients. Methods. A quantitative approach was employed to assess Acinetobacter baumannii infection in transfusion dependent thalassemia patients. Samples were collected from 916 patients, which have shown bacterial growth on MacConkey and blood agar culture media. A. baumannii strains were identified by microbiological methods and Gram’s staining. API 20 E kit (Biomerieux, USA) was used for final identification. Results. From 916 cultured blood specimens, 107 (11.6%) showed growth of A. baumannii. Serum ferritin in thalassemic patients without bacterial infections was µg/L versus µg/L in those with bacterial infections (). Acinetobacter baumannii infected patients have shown higher serum ferritin levels (). Serum ferritin in thalassemic patients was µg/L versus µg/L in those with bacterial infections (). Acinetobacter baumannii infected patients showed high serum ferritin levels (). The clinical symptoms have been found with A. baumannii +ve with a mean and standard deviation of 47 (5.1%) and A. baumannii −ve with mean and standard deviation of 60 (6.5%). Conclusion. Isolation of asymptomatic A. baumannii from the thalassemia patients shows an alarming situation of bacterial infections. A continuous surveillance of transfusion dependent thalassemia patients is recommended for bacterial sepsis.