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BioMed Research International
Volume 2017 (2017), Article ID 2352874, 7 pages
https://doi.org/10.1155/2017/2352874
Research Article

Genetic Variants in the Promoter Region of miR-10b and the Risk of Breast Cancer

1Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China
2Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Medicine, Nanjing Medical University, Nanjing, China
3State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 211166, China
4Department of Social Medicine and Health Education, School of Public Health, Nanjing Medical University, Nanjing, China

Correspondence should be addressed to Juncheng Dai

Received 1 March 2017; Accepted 14 May 2017; Published 12 June 2017

Academic Editor: Hushan Yang

Copyright © 2017 Jiaping Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. A. Torre, F. Bray, R. L. Siegel, J. Ferlay, J. Lortet-Tieulent, and A. Jemal, “Global cancer statistics, 2012,” CA:A Cancer Journal for Clinicians, vol. 65, no. 2, pp. 87–108, 2015. View at Publisher · View at Google Scholar
  2. W. Chen, R. Zheng, P. D. Baade et al., “Cancer statistics in China, 2015,” CA:A Cancer Journal for Clinicians, vol. 66, no. 2, pp. 115–132, 2016. View at Google Scholar
  3. P. Lichtenstein, N. V. Holm, P. K. Verkasalo et al., “Environmental and heritable factors in the causation of cancer: analyses of cohorts of twins from Sweden, Denmark, and Finland,” The New England Journal of Medicine, vol. 343, no. 2, pp. 78–85, 2000. View at Publisher · View at Google Scholar · View at Scopus
  4. P. G. Shields and C. C. Harris, “Cancer risk and low-penetrance susceptibility genes in gene-environment interactions,” Journal of Clinical Oncology, vol. 18, no. 11, pp. 2309–2315, 2000. View at Publisher · View at Google Scholar · View at Scopus
  5. J. Lu, G. Getz, E. A. Miska et al., “MicroRNA expression profiles classify human cancers,” Nature, vol. 435, no. 7043, pp. 834–838, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. G. A. Calin and C. M. Croce, “MicroRNA signatures in human cancers,” Nature Reviews Cancer, vol. 6, no. 11, pp. 857–866, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. B. D. Adams, A. L. Kasinski, and F. J. Slack, “Aberrant regulation and function of microRNAs in cancer,” Current Biology, vol. 24, no. 16, pp. R762–R776, 2014. View at Google Scholar
  8. G. Bertoli, C. Cava, C. Diceglie et al., “MicroRNA-567 dysregulation contributes to carcinogenesis of breast cancer, targeting tumor cell proliferation, and migration,” Breast Cancer Research and Treatment, vol. 161, no. 3, pp. 605–616, 2016. View at Publisher · View at Google Scholar · View at Scopus
  9. H. Peurala, D. Greco, T. Heikkinen et al., “MiR-34a expression has an effect for lower risk of metastasis and associates with expression patterns predicting clinical outcome in breast cancer,” PLoS ONE, vol. 6, no. 11, Article ID e26122, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. F. Rothé, M. Ignatiadis, C. Chaboteaux et al., “Global microRNA expression profiling identifies MiR-210 associated with tumor proliferation, invasion and poor clinical outcome in breast cancer,” PLoS ONE, vol. 6, no. 6, Article ID e20980, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. M. V. Iorio, M. Ferracin, C.-G. Liu et al., “MicroRNA gene expression deregulation in human breast cancer,” Cancer Research, vol. 65, no. 16, pp. 7065–7070, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. L. Ma, J. Teruya-Feldstein, and R. A. Weinberg, “Tumour invasion and metastasis initiated by microRNA-10b in breast cancer,” Nature, vol. 449, no. 7163, pp. 682–688, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. L. Ma, F. Reinhardt, E. Pan et al., “Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model,” Nature Biotechnology, vol. 28, no. 4, pp. 341–347, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. H. Xiao, H. Li, G. Yu et al., “MicroRNA-10b promotes migration and invasion through KLF4 and HOXD10 in human bladder cancer,” Oncology Reports, vol. 31, no. 4, pp. 1832–1838, 2014. View at Publisher · View at Google Scholar · View at Scopus
  15. C.-G. Liao, L.-M. Kong, P. Zhou, and et al., “MiR-10b is overexpressed in hepatocellular carcinoma and promotes cell proliferation, migration and invasion through RhoC, uPAR and MMPs,” Journal of Translational Medicine, vol. 12, no. 1, article 234, 2014. View at Publisher · View at Google Scholar · View at Scopus
  16. Y. Tian, A. Luo, Y. Cai et al., “MicroRNA-10b promotes migration and invasion through KLF4 in human esophageal cancer cell lines,” Journal of Biological Chemistry, vol. 285, no. 11, pp. 7986–7994, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. G. Li, Z. Wu, Y. Peng et al., “MicroRNA-10b induced by Epstein-Barr virus-encoded latent membrane protein-1 promotes the metastasis of human nasopharyngeal carcinoma cells,” Cancer Letters, vol. 299, no. 1, pp. 29–36, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. S. Liu, J. Sun, and Q. Lan, “TGF-β-induced miR10a/b expression promotes human glioma cell migration by targeting PTEN,” Molecular Medicine Reports, vol. 8, no. 6, pp. 1741–1746, 2013. View at Publisher · View at Google Scholar · View at Scopus
  19. J. Kim, A. N. Siverly, D. Chen et al., “Ablation of miR-10b suppresses oncogene-induced mammary tumorigenesis and metastasis and reactivates tumor-suppressive pathways,” Cancer Research, vol. 76, no. 21, pp. 6424–6435, 2016. View at Publisher · View at Google Scholar · View at Scopus
  20. B. M. Ryan, A. I. Robles, and C. C. Harris, “Genetic variation in microRNA networks: the implications for cancer research,” Nature Reviews Cancer, vol. 10, no. 6, pp. 389–402, 2010. View at Publisher · View at Google Scholar · View at Scopus
  21. S. Cammaerts, M. Strazisar, P. De Rijk, and J. Del Favero, “Genetic variants in microRNA genes: impact on microRNA expression, function, and disease,” Frontiers in Genetics, vol. 6, article 186, 2015. View at Publisher · View at Google Scholar
  22. F. Qian, Y. Feng, Y. Zheng et al., “Genetic variants in microRNA and microRNA biogenesis pathway genes and breast cancer risk among women of African ancestry,” Human Genetics, vol. 135, no. 10, pp. 1145–1159, 2016. View at Publisher · View at Google Scholar · View at Scopus
  23. Z. Hu, J. Liang, Z. Wang et al., “Common genetic variants in pre-microRNAs were associated with increased risk of breast cancer in Chinese women,” Human Mutation, vol. 30, no. 1, pp. 79–84, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. Z. Hu, J. Chen, T. Tian et al., “Genetic variants of miRNA sequences and non small cell lung cancer survival,” Journal of Clinical Investigation, vol. 118, no. 7, pp. 2600–2608, 2008. View at Publisher · View at Google Scholar
  25. A. E. Hoffman, T. Zheng, C. Yi et al., “microRNA miR-196a-2 and breast cancer: A genetic and epigenetic association study and functional analysis,” Cancer Research, vol. 69, no. 14, pp. 5970–5977, 2009. View at Publisher · View at Google Scholar · View at Scopus
  26. A. Upadhyaya, R. A. Smith, D. Chacon-Cortes et al., “Association of the microRNA-single nucleotide polymorphism rs2910164 in miR146a with sporadic breast cancer susceptibility: a case control study,” Gene, vol. 576, no. 1, part 1, pp. 256–260, 2016. View at Publisher · View at Google Scholar · View at Scopus
  27. Z. Qin, J. Xue, Y. He et al., “Potentially functional polymorphisms in ATG10 are associated with risk of breast cancer in a Chinese population,” Gene, vol. 527, no. 2, pp. 491–495, 2013. View at Publisher · View at Google Scholar · View at Scopus
  28. L. Vrba, J. C. Garbe, M. R. Stampfer, and B. W. Futscher, “Epigenetic regulation of normal human mammary cell type-specific miRNAs,” Genome Research, vol. 21, no. 12, pp. 2026–2037, 2011. View at Publisher · View at Google Scholar · View at Scopus
  29. S. A. Ibrahim, G. W. Yip, C. Stock et al., “Targeting of syndecan-1 by microRNA miR-10b promotes breast cancer cell motility and invasiveness via a Rho-GTPase- and E-cadherin-dependent mechanism,” International Journal of Cancer, vol. 131, no. 6, pp. E884–E896, 2012. View at Publisher · View at Google Scholar · View at Scopus
  30. P. N. Plummer, R. Freeman, R. J. Taft et al., “MicroRNAs regulate tumor angiogenesis modulated by endothelial progenitor cells,” Cancer Research, vol. 73, no. 1, pp. 341–352, 2013. View at Publisher · View at Google Scholar · View at Scopus
  31. X. Zhou, J. Ruan, G. Wang, and W. Zhang, “Characterization and identification of microRNA core promoters in four model species,” PLoS Computational Biology, vol. 3, no. 3, pp. 0412–0423, 2007. View at Publisher · View at Google Scholar · View at Scopus
  32. Y. Xu, L. Liu, J. Liu et al., “A potentially functional polymorphism in the promoter region of miR-34b/c is associated with an increased risk for primary hepatocellular carcinoma,” International Journal of Cancer, vol. 128, no. 2, pp. 412–417, 2011. View at Publisher · View at Google Scholar · View at Scopus
  33. Y. Liu, Y. Zhang, J. Wen et al., “A genetic variant in the promoter region of mir-106b-25 cluster and risk of hbv infection and hepatocellular carcinoma,” PLoS ONE, vol. 7, no. 2, Article ID e32230, 2012. View at Publisher · View at Google Scholar · View at Scopus
  34. X. Luo, W. Yang, D.-Q. Ye et al., “A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus,” PLoS Genetics, vol. 7, no. 6, Article ID e1002128, 2011. View at Publisher · View at Google Scholar · View at Scopus