Altered Erythropoiesis in Mouse Models of Type 3 Hemochromatosis
Perl’s Prussian blue staining of liver and spleen sections from wild type (WT), Tfr2 KI (KI), and Tfr2 KO (KO) animals at (a) 14 days (14 d) and (b) 10 weeks (10 w) of age. Western blot analysis shows ferritin L (Ft-L) protein production in bone marrow of WT, KI, and KO mice at (c) 14 days (14 d) and (d) 10 weeks (10 w) of age. a.u.: arbitrary unit. The following symbols indicate statistically significant differences: , , and compared to age-matched WT mice.
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