Copy Number Variations in Candidate Genes and Intergenic Regions Affect Body Mass Index and Abdominal Obesity in Mexican Children
Table 2
Anthropometric and clinical characteristics of participating children in the study.
Factor
Normal weight
Overweight
Obese
719 (50.5%)
308 (21.6%)
396 (27.9%)
Gender (%)
Male
378 (52.6)
144 (46.8)
221 (55.8)
Female
341 (47.4)
164 (53.3)
175 (44.2)
Age (years)
9 (7–11)
9 (8–11)
9 (8–11)
BMI (kg/m2)
16.4 (15.2–17.9)
20.3 (18.8–21.7)
24.1 (22–26.8)
<0.00
Waist circumference (cm)
57.6 (53.7–62.9)
68.1 (62.8–73.9)
78 (72.2–86.2)
<0.00
Abdominal obesity, (%)
No
694 (96.5)
191 (62)
31 (7.8)
<0.00
Yes
35 (3.5)
117 (38)
365 (92.2)
SBP (mmHg)
95 (90–100)
100 (90–105)
100.5 (95–110)
<0.00
DBP (mmHg)
65 (60–70)
69 (60–70)
70 (60–73)
<0.00
Glucose (mg/dl)
81 (75–87)
82 (77–88)
83 (77–89)
Cholesterol (mg/dl)
152 (132–175)
158 (137.5–177)
157.5 (136–181.5)
HDL-c (mg/dl)
54 (45–61)
49.5 (41–57.5)
43 (37–52)
<0.00
LDL-c (mg/dl)
96 (82–114)
104.5 (88–120)
105.5 (89.5–122)
<0.00
Triglycerides (mg/dl)
70 (55–90)
87.5 (66.5–119.5)
103 (76–147.5)
<0.00
Adiponectin (μg/ml)
14.5 (12.5–16.4)
14.1 (12.3–16.5)
13.6 (11.8–16.0)
Leptin (ng/ml)
10.2 (5.8–17.4)
22.4 (14.8–29.5)
30.9 (22.6–38.4)
<0.00
Insulin (μU/ml)
4.6 (2.6–7.4)
7.4 (4.3–11)
9.7 (4.8–16.2)
<0.00
HOMA-IR, (%)
<percentile 90
703 (97.7)
289 (93.8)
284 (71.7)
<0.00
≥percentile 90
16 (2.3)
19 (6.2)
112 (28.3)
Acanthosis, (%)
No
642 (89.3)
225 (73.1)
148 (37.4)
<0.00
Yes
77 (10.7)
83 (26.9)
248 (62.6)
T2D family history, (%)
No
655 (91.1)
268 (87)
340 (85.9)
Yes
64 (8.9)
40 (13)
56 (14.1)
Obesity family history, (%)
No
390 (54.2)
139 (45.1)
137 (34.6)
<0.00
Yes
329 (45.8)
169 (54.9)
259 (65.4)
Data are reported as medians (25th–75th) or as noted in table. -square test; Wallis test. BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HDL-c: high density lipoprotein-cholesterol; LDL-c: low density lipoprotein-cholesterol; HOMA-IR: homeostatic model assessment-insulin resistance; T2D: type 2 diabetes.
