TDF Monotherapy Is Effective Regardless of Prior Nucleos(t)ide Analogue Treatment in Chronic Hepatitis B Patients in China
ALT levels changes (a) and the rates of ALT normalizations (b) during antivirus therapy in each group. There was no significant difference in NA-naïve and NA-experienced group neither in ALT levels changes nor in ALT normalization rates. However, ALT level decreased significantly from week 0 to week 12 in both NA-naïve and NA-experienced group. ALT: Alanine aminotransferase; TDF: tenofovir disoproxil fumarate; NA: nucleos(t)ide analogue (all ).