Pharmacokinetic and Pharmacodynamic Evaluation of Marbofloxacin in Pig against Korean Local Isolates of Actinobacillus pleuropneumoniae

Table 5

Pharmacokinetic/pharmacodynamic integration of marbofloxacin in pig after administration through intravenous, intramuscular, and peroral routes.

Parameters	Units	i.v.	i.m.	p.o.
/MIC	h	253.86 ± 179.91	264.1 ± 187.16	239.53 ± 169.75
/MIC	—	26.58 ± 18.84	26.48 ± 18.77	23.94 ± 16.97
/MBC	h	144.93 ± 143.35	150.77 ± 149.13	136.74 ± 135.26
/MBC	—	15.18 ± 15.01	15.12 ± 14.95	13.67 ± 13.52
T > MIC	—	42.80 ± 1.010	36.40 ± 1.24	38.60 ± 1.18
AUC > MIC	—	20.90 ± 0.90	20.40 ± 1.40	26.50 ± 5.00

i.v.: intravenous, i.m.: intramuscular, and p.o.: peroral. Significantly different among groups.