Review Article

Comparative Study of Elastic Network Model and Protein Contact Network for Protein Complexes: The Hemoglobin Case

Figure 5

Square fluctuations of Hb monomers and tetramers. (a) Square fluctuations of subunits in isolated and tetrameric states based on the first 20 ANM modes. The differences of mobilities at and interfaces are indicated by red and green circles. (b) Square fluctuations of subunits in isolated and tetrameric states based on the first 20 ANM modes. Red, green, and black circles indicate the differences of mobilities at and interfaces and a common region of these two interfaces. (c) Square fluctuations of -Hb tetramers based on the highest two modes. Hot spots are predicted by the peaks in the profile, while and dimer show the same prediction result.
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