Effect of Wnt Signaling on the Differentiation of Islet β-Cells from Adipose-Derived Stem Cells

Figure 8

Western blot analysis of relative levels of insulin and Wnt pathway protein expression in rat ADSCs induced into insulin-producing cells over time (L3, H3, and H7) and in the presence of the Wnt-3a activator (W-L3, W-H3, and W-H7) or the DKK-1 inhibitor (D-L3, DH3, and D-H7). Data are presented as the mean ± standard deviation. and , compared with L3 (ADSCs cultured in the DMEM low glucose culture medium containing 1% DMSO for 3 days).