Research Article

Urinary Biomarker Panel to Improve Accuracy in Predicting Prostate Biopsy Result in Chinese Men with PSA 4–10 ng/mL

Table 1

Clinical characteristic of men with positive and negative biopsy.

Median (IQR)All patients value
Prostate cancerNegative biopsy

No. pts3389
Age, mean (SD), years68.4 (6.7)64.1 (7.7)
PSA, mean (SD), ng/mL7.0 (1.7)7.2 (1.7)
Prostate volume, mL51.6 (38.2, 69.7)39.9 (28.0, 55.9)
% fPSA, %15.0 (10.6, 18.5)17.0 (13.3 to 22.7)
PCA3125.0 (48.4, 252.7)51.5 (14.5 to 104.7)
PSGR160.3 (111.5, 298.9)105.8 (32.9 to 187.0)
PSMA62.7 (22.5, 120.9)69.2 (25.4, 116.0)
MALTA-1160.3 (101.4 to 499.5)85.5 (31.1 to 151.8)
Positive DRE11/3320/89

IQR: interquartile range; no. pts: number of patients; PSA: prostate-specific antigen; % fPSA: percent free PSA; PCA3: prostate cancer antigen 3; PSGR: prostate-specific G protein coupled receptor; PSMA: prostate-specific membrane antigen; MALAT-1: metastasis-associated lung adenocarcinoma transcript 1; : Mann–Whitney test; : independent sample test; : chi-square test.