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BioMed Research International
Volume 2017 (2017), Article ID 2565397, 7 pages
https://doi.org/10.1155/2017/2565397
Clinical Study

Prospective Multicentre Study on the Epidemiology and Current Therapeutic Management of Severe Bronchiolitis in Spain

1Unidad de Cuidados Intensivos Pediátricos, Hospital Universitario Puerta del Mar, Cádiz, Spain
2Sección de Cuidados Intensivos Pediátricos, Hospital Universitario Central de Asturias, Oviedo, Spain
3Unidad de Cuidados Intensivos Pediátricos, Hospital Sant Joan de Déu Barcelona, Barcelona, Spain
4Unidad de Cuidados Intensivos Pediátricos, Hospital de Burgos, Burgos, Spain
5Unidad de Cuidados Intensivos Pediátricos, Hospital Universitario Virgen Del Rocío, Sevilla, Spain
6Unidad de Cuidados Intensivos Pediátricos, Hospital 12 de Octubre, Madrid, Spain
7Unidad de Cuidados Intensivos Pediátricos, Hospital Universitario Gregorio Marañón, Madrid, Spain
8Unidad de Cuidados Intensivos Pediátricos, Hospital Universitario Donostia, San Sebastián, Spain
9Unidad de Cuidados Intensivos Pediátricos, Hospital Universitario de Salamanca, Salamanca, Spain
10Unidad de Cuidados Intensivos Pediátricos, Hospital de Jaén, Jaén, Spain
11Unidad de Cuidados Intensivos Pediátricos, Hospital Clínico San Carlos, Madrid, Spain
12Unidad de Cuidados Intensivos Pediátricos, Hospital General Universitario de Alicante, Alicante, Spain
13Unidad de Cuidados Intensivos Pediátricos, Hospital Universitario Regional de Málaga, Málaga, Spain
14Unidad de Cuidados Intensivos Pediátricos, Hospital Virgen de la Salud, Toledo, Spain
15Unidad de Cuidados Intensivos Pediátricos, Hospital Virgen de la Arrixaca, Murcia, Spain
16Unidad de Cuidados Intensivos Pediátricos, Complejo Hospitalario de Pamplona, Pamplona, Spain

Correspondence should be addressed to Jose C. Flores-González; moc.liamg@nogolfsolrac

Received 26 November 2016; Revised 14 February 2017; Accepted 27 February 2017; Published 22 March 2017

Academic Editor: Paolo Spagnolo

Copyright © 2017 Jose C. Flores-González et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. To determine the epidemiology and therapeutic management of patients with severe acute bronchiolitis (AB) admitted to paediatric intensive care units (PICUs) in Spain. Design. Descriptive, prospective, multicentre study. Setting. Sixteen Spanish PICUs. Patients. Patients with severe AB who required admission to any of the participating PICUs over 1 year. Interventions. Both epidemiological variables and medical treatment received were recorded. Results. A total of 262 patients were recruited; 143 were male (54.6%), with median age of 1 month (0–23). Median stay in the PICU was 7 days (1–46). Sixty patients (23%) received no nebuliser treatment, while the rest received a combination of inhalation therapies. One-quarter of patients (24.8%) received corticosteroids and 56.5% antibiotic therapy. High-flow oxygen therapy was used in 14.3% and noninvasive ventilation (NIV) was used in 75.6%. Endotracheal intubation was required in 24.4% of patients. Younger age, antibiotic therapy, and invasive mechanical ventilation (IMV) were risk factors that significantly increased the stay in the PICU. Conclusions. Spanish PICUs continue to routinely use nebulised bronchodilator treatment and corticosteroid therapy. Despite NIV being widely used in this condition, intubation was required in one-quarter of cases. Younger age, antibiotic therapy, and IMV were associated with a longer stay in the PICU.