BioMed Research International / 2017 / Article / Fig 5

Research Article

The Proangiogenic Capabilities of Malignant Ascites Generated by Aggressive Ovarian Tumors

Figure 5

Effect of malignant ascites from clear cell (CC), endometrioid (Endo), serous (Ser), and undifferentiated (Undiff) ovarian tumors on the proliferation (a) and migration (b) of EA.hy926 endothelial cells, and on the concentration of transcription factor HIF-1α in these cells (c). versus BA; versus CC/Endo; versus Ser. The experiments were performed with both malignant and benign ascites obtained from 6 patients per group. The endothelial cells were used in quadruplicates. The results are expressed as mean ± SEM. BA: benign ascites; RFU: relative fluorescence units.

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