Research Article

The Proangiogenic Capabilities of Malignant Ascites Generated by Aggressive Ovarian Tumors

Table 1

Concentration of soluble proangiogenic agents in conditioned medium harvested from endothelial cells exposed to benign peritoneal ascites and to malignant ascites from patients with clear cell, endometrioid, serous, and undifferentiated ovarian cancer.

Soluble factor (pg/105 cells)Benign fluidsType I cancersType II cancers
Clear cellEndometrioidSerousUndifferentiated

EGF
FGF2
GRO-1
HGF
IL-8
MCP-1
VEGF

The results derive from an analysis of tumors from 8 different patients per group and are expressed as mean ± SEM. versus benign fluids; versus clear cell; versus endometrioid; versus serous.