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BioMed Research International
Volume 2017, Article ID 2679148, 9 pages
https://doi.org/10.1155/2017/2679148
Clinical Study

Restrictive Transfusion Strategy Does Not Affect Clinical Prognosis in Patients with Ectopic Pregnancy

1Department of Anesthesiology, Third Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi 530031, China
2Department of Cardiology, Third Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi 530031, China
3Department of Gynecology, Third Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi 530031, China

Correspondence should be addressed to Yanjuan Huang; moc.361@66naujnaygnauh

Received 10 March 2017; Revised 28 September 2017; Accepted 5 November 2017; Published 16 November 2017

Academic Editor: Ivo Meinhold-Heerlein

Copyright © 2017 Yanjuan Huang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

To assess the effects of restrictive transfusion strategy on hemoglobin (Hb) levels and prognosis in patients with ectopic pregnancy and severe hemorrhage undergoing emergency surgery, patient data were collected from 2012 to 2016. Following transfusion guidelines, restrictive transfusion was performed; at Hb levels of 60–70 to 100 g/L, transfusion was continued or not based on disease status. The patients were divided into four groups: blood loss < 400 ml (N1), 400–799 ml (N2), 800–1199 ml (N3), and ≥1200 ml (N4). Several prognosis parameters were assessed. Group N4 was further divided based on blood loss amounts (1200–1999, 2000–2999, 3000–3999, and 4000–5000 ml) for subgroup analyses. Blood loss, hemoglobin levels at discharge, and American Society of Anesthesiologists (ASA) scores were not associated with patient prognostic parameters, including intensive care unit (ICU) occupancy, cure, and healing rates, and surgical complications and hospital stay. No statistically significant difference was obtained in hospital stay among N1, N2, and N3 groups. Compared with N1 patients, cases with blood loss ≥ 1200 ml had significantly longer hospital stay. Interestingly, hospital stay was correlated with surgical approach, location of pregnancy, and operation time. Restrictive transfusion strategy could be safely used for emergency surgery in ectopic pregnancy with acute blood loss.