Clinical Study

The Association of Serum Thrombomodulin with Endothelial Injuring Factors in Abdominal Aortic Aneurysm

Table 4

Comparison between AAA patients categorized into quartiles according to sTM concentration.

sTM (ng/mL)
Quartile I (sTM concentration < 2.19)Quartiles II and III (sTM concentration 2.19–5.69)Quartile IV (sTM concentration > 5.69) value

Age72.14 ± 10.9571.29 ± 9.9672.57 ± 8.30
BMI27.64 ± 6.2027.17 ± 3.6330.61 ± 7.43
Aneurysm diameter
(mm)
66
(55–74)
66
(56–72)
59
(52–63)
Systolic blood pressure
(mm Hg)
138
(135–163)
135
(120–142)
125
(120–145)
Diastolic blood pressure
(mm Hg)
90
(82–90)
80
(80–85)
75
(59–83)
WBC (109/L)7.84 ± 3.947.67 ± 2.317.99 ± 2.60
RBC (1012/L)4.51
(4.33–4.58)
4.58
(4.34–5.14)
4.98
(4.38–5.28)
PLT (109/L)321 ± 186218 ± 54255 ± 61
Fibrinogen (mg/dL)295
(284–385)
280
(262–328)
418
(228–436)
Uric acid
(µM)
346
(312–356)
363
(319–412)
367
(316–399)
TAG
(mM)
1.16 ± 0.441.30 ± 0.592.83 ± 1.70
Cholesterol
(mM)
4.36
(3.23–4.81)
4.18 
(3.13–4.43)
4.90
(4.62–4.97)
LDL-cholesterol
(mM)
2.40
(1.15–3.30)
2.15 
(1.47–2.90)
2,30
(1.15–3.00)
HDL-cholesterol
(mM)
1.61 ± 0.691.22 ± 0.401.21 ± 0.24
hsCRP
(mg/L)
12.03
(6.87–15.53)
5.64
(1.25–11.00)
16.72
(7.72–23.26)
AOPP
(µM/mg protein)
6.14
(4.06–8.03)
4.10
(2.74–6.60)
4.74
(3.83–6.08)
AGEs
(µg/mg protein)
0.17
(0.11–0.19)
0.22
(0.11–0.19)
0.23
(0.16–0.46)
RAGE
(pg/mg protein)
1.81
(0.86–2.01)
0.75
(0.41–1.48)
0.71
(0.59–1.63)
Carbonyl groups
(nM/mg protein)
0.88
(0.70–1.34)
0.93
(0.71–1.00)
1.03
(0.66–1.98)

Results shown as median and interquartile range, comparison done by using Kruskal-Wallis test; results shown as mean ± standard deviation, comparison done by using one-way ANOVA test.
BMI: body mass index, WBC: white blood cells, RBC: red blood cells, PLT: blood platelets, TAG: triglycerides, hsCRP: highly sensitive C-reactive protein, AOPP: advanced oxidation protein products, AGEs: advanced glycation end products, and sRAGE: soluble receptors for advanced glycation end products.