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BioMed Research International
Volume 2017, Article ID 2841549, 5 pages
https://doi.org/10.1155/2017/2841549
Research Article

Anxiolytics, Sedatives, and Hypnotics Prescribed by Dentists in Brazil in 2010

1Department of Community and Preventive Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
2Department of Pharmaceutical Products, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
3Department of Operative Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil

Correspondence should be addressed to Mauro Henrique Nogueira Guimar√£es de Abreu; moc.liamg@uerbaeuqirnehoruam

Received 17 January 2017; Accepted 14 May 2017; Published 30 May 2017

Academic Editor: Jane Hanrahan

Copyright © 2017 Patrícia Azevedo Lino et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. To describe dental prescriptions for anxiolytics, sedatives, and hypnotics for Brazilian outpatients in 2010. Methods. A cross-sectional study was conducted using data on the use of anxiolytics, sedatives, and hypnotics from the Brazilian Health Surveillance Agency, Brazil, 2010. For each prescription, prescribed drugs and the prescribed amount were identified. Prescribed medications were classified according to Anatomical Therapeutic Chemical code. We calculated the number of Defined Daily Doses (DDD) for anxiolytics, sedatives, and hypnotics by code, their mean DDD, and DDD per inhabitant per year. Results. There were 16,436 prescriptions dispensed, including anxiolytics, sedatives, and hypnotics. These prescriptions corresponded to 3,555,780.50 mg, distributed as 2,286,200.50 mg (64.30%) of anxiolytics and 1,269,580.00 mg (35.70%) of sedatives and hypnotics. This amount allowed treating approximately 474,106 individuals (number of DDD). The anxiolytics most frequently dispensed were bromazepam (25.30%), alprazolam (19.19%), and diazepam (15.60%). Sedatives and hypnotics mostly prescribed were zolpidem (9.55%), midazolam (6.99%), and flunitrazepam (2.14%). The per capita rates (100,000 inhabitants) of anxiolytics and sedatives/hypnotics were 6.83 and 1.78, respectively. Conclusions. Benzodiazepines and derivatives were the most frequently prescribed drugs. There was a low rate of dental prescriptions for anxiolytics, sedatives, and hypnotics, although excessive doses were concentrated in the same prescription.