Research Article

Anxiolytics, Sedatives, and Hypnotics Prescribed by Dentists in Brazil in 2010

Table 1

Anxiolytics, sedatives, and hypnotics prescribed by dentists in Brazil in 2010.

ATC nameTotal mgNumber of DDDMean of DDDDDD per inhabitant
per year
Number of drug boxesMean
(minimum–maximum)
number of boxes
Number (%) of dispensed
drugs
Per capita rate
(100,000 inhabitants)

Alprazolam 117,787.50 117,787.50 37.35 0.000617485,6721.80 (1–12)3,154 (19.19%) 1.653
Bromazepam 918,423.00 91,842.30 22.09 0.000481477,9311.75 (1–15)4,158 (25.30%) 2.180
Buspirone 49,100.00 1,636.67 8.14 0.000008583471.73 (1–6)201 (1.22%) 0.105
Chlordiazepoxide 2,600.00 86.67 28.89 0.0000004572.33 (2-3)3 (0.02%) 0.002
Clobazam 110,600.00 5,530.00 28.36 0,000028994262.18 (1–6)195 (1.19%) 0.102
Cloxazolam 96,270.00NCNCNC2,4191.66 (1–6)1,458 (8.87%) 0.764
Diazepam 848,550.00 84,855.00 34.27 0.000444844,2951.73 (1–10)2,476 (15.06%) 1.298
Lorazepam 142,870.00 57,148.00 41.17 0.000299593,1332.26 (1–9)1,388 (8.44%) 0.728

Total anxiolytics 2,286,200.50 358,886.13 27.54 0.0018813924,2301.86 (1–15)13.033 (79.30%) 6.832

Midazolam 560,770.00 37,384.67 32.54 0.000195981,5171.32 (1–15)1,149 (6.99%) 0.602
Estazolam 4,900.00 1,633.33 24.75 0.000008561211.83 (1–5)66 (0.40%) 0.035
Flunitrazepam 20,090.00 20,090.00 57.24 0.000105326771.93 (1–8)351 (2.14%) 0.184
Flurazepam 207,900.00 6,930.00 54.14 0.000036332311.80 (1–5)128 (0.78%) 0.067
Nitrazepam 9,900.00 1,980.00 38.08 0.00001038991.90 (1–3)52 (0.32%) 0.027
Zolpidem 448,020.00 44,802.00 28.54 0.000234872,3891.52 (1–9)1570 (9.55%) 0.823
Zopiclone 18,000.00 2,400.00 27.59 0.000012581201.38 (1–3)87 (0.53%) 0.046

Total hypnotics and sedatives 1,269,580.00 115,220.00 33.86 0.000604025,1541.51 (1–15)3403 (20.70%) 1.784

Total mg/DDD value; number of DDD/number of dispensed drugs; NC: drug with no DDD available.