Research Article

Bioinformatics Analysis Reveals MicroRNAs Regulating Biological Pathways in Exercise-Induced Cardiac Physiological Hypertrophy

Table 2

The KEGG pathways incorporated by downregulated miRNAs.

KEGG pathwayGenes

Fatty acid elongation4.84Hadha, Elovl6
Arrhythmogenic right ventricular cardiomyopathy (ARVC)2.94Cacng4, Cacna2d1, Sgcd, Jup, Itgb8, Gja1
Other types of O-glycan biosynthesis2.34B3glct, Pomt2, Fut9, Colgalt2
Thyroid hormone synthesis2.04Duox2, Tg
Tyrosine metabolism2.04Maoa, Aldh1a3
Mucin type O-Glycan biosynthesis1.76Galnt16, Galnt7
Other glycan degradation1.66Neu3
Glycosphingolipid biosynthesis-lacto and neolacto series1.66B3galt2, Fut9
Tryptophan metabolism1.66Afmid, Hadha, Tph2, Maoa, Ogdhl
Gap junction1.66Tjp1, Egfr, Nras, Grm5, Gja1
Proteoglycans in cancer1.66Wnt2, Cttn, Wnt4, Fgfr1, Egfr, Fn1, Nras, Erbb3, Rock2, Flna, Fzd3, Wnt2b, Pik3cd, Cav3, Ppp1cc
Signaling pathways regulating pluripotency of stem cells1.57Fgfr3, Wnt2, Wnt4, Fgfr1, Nras, Nodal, Smad4, Fzd3, Wnt2b, Pik3cd, Acvr1c